(Q34044585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Michael P Maher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Ronald V Swanson

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Wilson Edwards

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Chichi Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Ellen Chi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Nancy Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Yi Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Rachelle Bonesteel

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Judith Connor

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Ross Fellows

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Elena Garcia

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Jerry Lee

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Lu Lu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Karen Ngo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Brian Scott

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Hong Zhou

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Alan D Wickenden

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

language of work or name

English

0 references

publication date

17 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

22704-22714

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

Therapeutic potential of cone snail venom peptides (conopeptides).

20 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Venoms as a platform for human drugs: translating toxins into therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

The functional network of ion channels in T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

How many drug targets are there?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Kv1.3 potassium channel blockade as an approach to insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Intrathecal ziconotide for refractory pain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Selective blocking of voltage-gated K+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Repeating functional domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

Sequence-imposed structural constraints in the TonB protein of E. coli.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132777

The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

Transfer of the scorpion toxin receptor to an insensitive potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

Tacrolimus versus cyclosporine induction therapy in pulmonary transplantation in miniature swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

Long-term survival of an allografted submandibular gland in a miniature swine model given immunosuppressant drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

Immunization with an interferon-gamma-gp120 fusion protein induces enhanced immune responses to human immunodeficiency virus gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.568642

1H-NMR study of mobility and conformational constraints within the proline-rich N-terminal of the LC1 alkali light chain of skeletal myosin. Correlation with similar segments in other protein systems

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24939846

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Restructuring an interdomain linker in the dihydrolipoamide acetyltransferase component of the pyruvate dehydrogenase complex of Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24939846

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.568642

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939846%20AND%20SRC:MED&resulttype=core&format=json