(Q34277605)

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Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

based on heuristic

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autoimmune disease

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based on heuristic

inferred from title

Christine Beeton

object named as

Christine Beeton

20

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Michael W Pennington

object named as

Michael W Pennington

19

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ShK toxin: history, structure and therapeutic applications for autoimmune diseases

21

object named as

K George Chandy

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1 August 2017

author name string

Eric J Tarcha

1

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1 August 2017

Victor Chi

2

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1 August 2017

Ernesto J Muñoz-Elías

3

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1 August 2017

David Bailey

4

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1 August 2017

Luz M Londono

5

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Europe PubMed Central

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1 August 2017

Sanjeev K Upadhyay

6

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1 August 2017

Kayla Norton

7

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1 August 2017

Amy Banks

8

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1 August 2017

Indra Tjong

9

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1 August 2017

Hai Nguyen

10

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1 August 2017

Xueyou Hu

11

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1 August 2017

Greg W Ruppert

12

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1 August 2017

Scott E Boley

13

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1 August 2017

Richard Slauter

14

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Europe PubMed Central

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1 August 2017

James Sams

15

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Europe PubMed Central

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1 August 2017

Brian Knapp

16

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Europe PubMed Central

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1 August 2017

Dustin Kentala

17

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Europe PubMed Central

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1 August 2017

Zachary Hansen

18

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Europe PubMed Central

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1 August 2017

Shawn P Iadonato

22

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1 August 2017

language of work or name

0 references

publication date

25 May 2012

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Europe PubMed Central

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1 August 2017

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

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1 August 2017

342

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Europe PubMed Central

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1 August 2017

3

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1 August 2017

642-653

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Europe PubMed Central

PubMed publication ID

1 August 2017

Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21cip1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Voltage-gated potassium channel Kv1.3 blocker as a potential treatment for rat anti-glomerular basement membrane glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

The functional network of ion channels in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Kv1.3 potassium channels as a therapeutic target in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Induction and monitoring of active delayed type hypersensitivity (DTH) in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Recurrence phenomena after immunoglobulin therapy for snake envenomations: Part 1. Pharmacokinetics and pharmacodynamics of immunoglobulin antivenoms and related antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

An essential binding surface for ShK toxin interaction with rat brain potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

A three-compartment open pharmacokinetic model can explain variable toxicities of cobra venoms and their alpha toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Characterization of a potassium channel toxin from the Caribbean sea anemone Stichodactyla helianthus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Chronic relapsing experimental allergic encephalomyelitis in the Lewis rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Loss of alpha-bungarotoxin from junctional and extrajunctional acetylcholine receptors in rat diaphragm muscle in vivo and in organ culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Suppression of acute and chronic experimental allergic encephalomyelitis in Strain 13 guinea pigs. A clinical and pathological study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

Chronic relapsing experimental allergic encephalomyelitis: effect of age at the time of sensitization on clinical course and pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

The effect of Cop 1, a synthetic polypeptide, on chronic relapsing experimental allergic encephalomyelitis in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

6 July 2018

The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

28 October 2018

Blockade of T-lymphocyte KCa3.1 and Kv1.3 channels as novel immunosuppression strategy to prevent kidney allograft rejection

1 reference

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28 October 2018

Detection of arthritis-susceptibility loci, including Ncf1, and variable effects of the major histocompatibility complex region depending on genetic background in rats

1 reference

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28 October 2018

Characterization of the functional properties of the voltage-gated potassium channel Kv1.3 in human CD4+ T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422530

28 October 2018

Megalin is essential for renal proximal tubule reabsorption of (111)In-DTPA-octreotide.

1 reference

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28 October 2018

Receptor-mediated radionuclide therapy with 90Y-DOTATOC in association with amino acid infusion: a phase I study

1 reference

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28 October 2018

Enzyme-linked immunosorbent assay for the detection of Bothrops jararaca venom

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indication for different mechanisms of kidney uptake of radiolabeled peptides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF Production in Macrophages Is Genetically Determined and Regulates Inflammatory Disease in Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Randomized Multicenter Trial of Crotalinae Polyvalent Immune Fab (Ovine) Antivenom for the Treatment for Crotaline Snakebite in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turnover of junctional and extrajunctional acetylcholine receptors of the rat diaphragm

1 reference

https://pubmed.ncbi.nlm.nih.gov/22637724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/JPET.112.191890

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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