(Q35170845)

6 August 2017

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title

Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation (English)

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6 August 2017

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Bruno Lomonte

3

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José María Gutiérrez

object named as

José María Gutiérrez

series ordinal

1

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Guillermo León

series ordinal

2

object named as

Guillermo León

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6 August 2017

publication date

1 January 2003

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Clinical Pharmacokinetics

6 August 2017

published in

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6 August 2017

volume

42

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6 August 2017

issue

8

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6 August 2017

page(s)

721-741

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https://scigraph.springernature.com/pub.10.2165/00003088-200342080-00002

6 August 2017

exact match

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cites work

A randomized, blinded, comparative trial of one pepsin-digested and two whole IgG antivenoms for Bothrops snake bites in Uraba, Colombia. The Regional Group on Antivenom Therapy Research (REGATHER)

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12 December 2020

Use of enzyme immunoassays to compare the effect and assess the dosage regimens of three Brazilian Bothrops antivenoms. The Butantan Institute Antivenom Study Group (BIASG)

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12 December 2020

Treatment of snake bites by Bothrops species and Lachesis muta in Ecuador: laboratory screening of candidate antivenoms

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Kinetics of the Fab fragments of digoxin antibodies and of bound digoxin in patients with severe digoxin intoxication.

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12 December 2020

Are the toxicological effects of scorpion envenomation related to tissue venom concentration?

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12 December 2020

Plasma clearance time of Russell's viper (Vipera russelli) antivenom in human snake bite victims.

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12 December 2020

Progress in the characterization of venoms and standardization of antivenoms

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An affinity purified ovine antivenom for the treatment of Vipera berus envenoming

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12 December 2020

A randomized double-blind clinical trial of two antivenoms in patients bitten by Bothrops atrox in Colombia

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12 December 2020

Neurotoxicity, haemostatic disturbances and haemolytic anaemia after a bite by a Tunisian saw-scaled or carpet viper (Echis 'pyramidum'-complex): failure of antivenom treatment.

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12 December 2020

Metalloproteinase inhibitors in snakebite envenomations

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12 December 2020

Immunoglobulin G, F(AB')2, and fab fragment uptake kinetics in isolated perfused rat liver and rat hepatic cells

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12 December 2020

Clinical significance of venom antigen levels in patients envenomed by the Malayan pit viper (Calloselasma rhodostoma)

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12 December 2020

Snake antivenoms from hyperimmunized horses: comparison of the antivenom activity and biological properties of their whole IgG and F(ab')2 fragments

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12 December 2020

Recurrent and persistent coagulopathy following pit viper envenomation

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12 December 2020

Kinetics of envenomation with Russell's viper (Vipera russelli) venom and of antivenom use in mice

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12 December 2020

Effects of antivenom on Buthus occitanus tunetanus (Bot) scorpion venom pharmacokinetics: towards an optimization of antivenom immunotherapy in a rabbit model

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12 December 2020

Snake F(ab')2 antivenom from hyperimmunized horse: pharmacokinetics following intravenous and intramuscular administrations in rabbits.

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12 December 2020

Reversal of snake neurotoxin binding to mammalian acetylcholine receptor by specific antiserum

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12 December 2020

The development and use of immunotherapy in Africa

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12 December 2020

Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom

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12 December 2020

Hemorrhagic metalloproteinases from snake venoms

1 reference

12 December 2020

Neurotoxin-specific immunoglobulins accelerate dissociation of the neurotoxin-acetylcholine receptor complex

1 reference

12 December 2020

Time factor in the detection of circulating whole venom and crotoxin and efficacy of antivenom therapy in patients envenomed by Crotalus durissus

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12 December 2020

Antivenom therapy in the Americas

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12 December 2020

Immunoreactivity and pharmacokinetics of horse anti-scorpion venom F(ab')2-scorpion venom interactions

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12 December 2020

Efficacy of bothropic antivenom and its IgG(T) fraction in restoring fibrinogen levels of Bothrops jararaca envenomed mice

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12 December 2020

Alpha-latrotoxin: from structure to some functions.

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12 December 2020

Heterologous antisera and antivenins are essential biologicals: perspectives on a worldwide crisis

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12 December 2020

Digoxin-specific Fab fragments impair renal function in the rabbit

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12 December 2020

Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits

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12 December 2020

Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper

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12 December 2020

Identification of the sites of IgG catabolism in the rat

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12 December 2020

First clinical experiences with a new ovine Fab Echis ocellatus snake bite antivenom in Nigeria: randomized comparative trial with Institute Pasteur Serum (Ipser) Africa antivenom.

1 reference

12 December 2020

Ultrastructural alterations in mouse capillary blood vessels after experimental injection of venom from the snake Bothrops asper (Terciopelo).

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12 December 2020

A new monospecific ovine Fab fragment antivenom for treatment of envenoming by the Sri Lankan Russell's viper (Daboia Russelii Russelii): a preliminary dose-finding and pharmacokinetic study

1 reference

12 December 2020

Effect of antivenom on venom pharmacokinetics in experimentally envenomed rabbits: toward an optimization of antivenom therapy

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12 December 2020

Clinical indicators of envenoming and serum levels of venom antigens in patients bitten by Bothrops lanceolatus in Martinique. Research Group on Snake Bites in Martinique

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12 December 2020

Comparison of the purity and efficacy of affinity purified avian antivenoms with commercial equine crotalid antivenoms

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12 December 2020

Comparison between IgG and F(ab′)2 polyvalent antivenoms: neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions

1 reference

12 December 2020

Antivenoms: A list of hyperimmune sera currently available for the treatment of envenoming by bites and stings

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12 December 2020

Snake-bites: appraisal of the global situation

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12 December 2020

Neutralization of dermonecrotic and lethal activities and differences among 32-35 kDa toxins of medically important Loxosceles spider venoms in Brazil revealed by monoclonal antibodies

1 reference

12 December 2020

Recurrent coagulopathy after antivenom treatment of crotalid snakebite

1 reference

12 December 2020

Intradermal anti-loxosceles Fab fragments attenuate dermonecrotic arachnidism

1 reference

12 December 2020

Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibitor batimastat and the chelating agent CaNa2EDTA

1 reference

12 December 2020

Randomized comparative trial of three antivenoms in the treatment of envenoming by lance-headed vipers (Bothrops jararaca) in São Paulo, Brazil

1 reference

12 December 2020

Production and partial characterization of monoclonal antibodies to Bothrops asper (terciopelo) myotoxin

1 reference

12 December 2020

Preclinical assessment of immunoreactivity of a new purified equine F(ab')2 against European viper venom

1 reference

12 December 2020

Neutralization of myonecrosis, hemorrhage, and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice

1 reference

12 December 2020

An open, randomized comparative trial of two antivenoms for the treatment of envenoming by Sri Lankan Russell's viper (Daboia russelii russelii).

1 reference

12 December 2020

Fab fragments of the monoclonal antibody BCF2 are capable of neutralizing the whole soluble venom from the scorpion Centruroides noxius Hoffmann.

1 reference

12 December 2020

Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom

1 reference

12 December 2020

Absorption and elimination of viper venom after antivenom administration

1 reference

12 December 2020

Serum reactions. An analysis of commercial antivenoms and the possible role of anticomplementary activity in de-novo reactions to antivenoms and antitoxins

1 reference

12 December 2020

Paralysis, rhabdomyolysis and haemolysis caused by bites of Russell's viper (Vipera russelli pulchella) in Sri Lanka: failure of Indian (Haffkine) antivenom

1 reference

12 December 2020

Immunoenzymatic quantitation of antibodies to Bothrops asper myotoxins after polyvalent antivenom administration in mice

1 reference

12 December 2020

The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: An intravital and electron microscopic study

1 reference

12 December 2020

Pharmacokinetics of 125I-labelled IgG, F(ab')2 and Fab fractions of scorpion and snake antivenins: merits and potential for therapeutic use

1 reference

12 December 2020

Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage

1 reference

12 December 2020

Development of immunoassays for determination of circulating venom antigens during envenomations by coral snakes (Micrurus species)

1 reference

12 December 2020

Experimental treatment protocols for scorpion envenomation: A review of common therapies and an effect of kallikrein-kinin inhibitors

1 reference

12 December 2020

Immunogenicity and kinetics of distribution and elimination of sheep digoxin-specific IgG and Fab fragments in the rabbit and baboon

1 reference

12 December 2020

Neutralization of coral snake Micrurus nigrocinctus venom by a monovalent antivenom

1 reference

12 December 2020

Comparative study on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom

1 reference

12 December 2020

Quantitative comparison on the refinement of horse antivenom by salt fractionation and ion-exchange chromatography

1 reference

12 December 2020

The plasma disposition and renal elimination of digoxin-specific Fab fragments and digoxin in the rabbit

1 reference

12 December 2020

Pharmacokinetics of 125I-labelled Walterinnesia aegyptia venom and its distribution of the venom and its toxin versus slow absorption and distribution of IGG, F(AB')2 and F(AB) of the antivenin

1 reference

12 December 2020

Immunoglobulin G and F(ab′)2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom

1 reference

12 December 2020

Anti-digoxin Fab fragments in cardiotoxicity induced by ingestion of yellow oleander: a randomised controlled trial

1 reference

12 December 2020

Discovery of antitoxins and development of antibody preparations for clinical uses from 1890 to 1990.

1 reference

12 December 2020

Pharmacokinetics of Tityus serrulatus scorpion venom determined by enzyme-linked immunosorbent assay in the rat

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12 December 2020

Standardization of assays for testing the neutralizing ability of antivenoms

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12 December 2020

Peptides and genes coding for scorpion toxins that affect ion-channels.

1 reference

12 December 2020

Recurrence phenomena after immunoglobulin therapy for snake envenomations: Part 1. Pharmacokinetics and pharmacodynamics of immunoglobulin antivenoms and related antibodies.

1 reference

12 December 2020

A Randomized Multicenter Trial of Crotalinae Polyvalent Immune Fab (Ovine) Antivenom for the Treatment for Crotaline Snakebite in the United States

1 reference

12 December 2020

Rattlesnake and scorpion antivenoms from the egg yolks of immunized hens

1 reference

12 December 2020

Binding kinetics of monomeric and aggregated IgG to Kupffer cells and hepatocytes of mice

1 reference

12 December 2020

The scorpion envenoming syndrome

1 reference

12 December 2020

Pharmacokinetics of three commercial antivenoms in patients envenomed by the Malayan pit viper, Calloselasma rhodostoma, in Thailand.

1 reference

12 December 2020

Prediction, prevention, and mechanism of early (anaphylactic) antivenom reactions in victims of snake bites

1 reference

12 December 2020

Serum kinetics of crotoxin from Crotalus durissus terrificus venom in mice: evidence for a rapid clearance

1 reference

12 December 2020

Pharmacokinetics of monoclonal immunoglobulin G1, F(ab')2, and Fab' in mice

1 reference

12 December 2020

Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica

1 reference

12 December 2020

Antibody treatment of toxin poisoning--recent advances

1 reference

12 December 2020

Randomized comparative trial of three monospecific antivenoms for bites by the Malayan pit viper (Calloselasma rhodostoma) in southern Thailand: clinical and laboratory correlations

1 reference

12 December 2020

Development of a sensitive radioimmunoassay for Fab fragments: application to Fab pharmacokinetics in humans

1 reference

12 December 2020

Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper

1 reference

12 December 2020

Pharmacokinetics of the toxic fraction of Centruroides limpidus limpidus venom in experimentally envenomed rabbits and effects of immunotherapy with specific F(ab')2

1 reference

12 December 2020

Recurrence phenomena after immunoglobulin therapy for snake envenomations: Part 2. Guidelines for clinical management with crotaline Fab antivenom.

1 reference

12 December 2020

Efficacy of antivenom therapy for neutralizing circulating venom antigens in patients stung by Tityus serrulatus scorpions

1 reference

12 December 2020

Envenoming by viper bites in France: clinical gradation and biological quantification by ELISA

1 reference

12 December 2020

Reversion by polyclonal antibodies of alpha effects of Tityus serrulatus venom on frog sciatic nerve

1 reference

12 December 2020

Caprylic acid fractionation of hyperimmune horse plasma: Description of a simple procedure for antivenom production

1 reference

12 December 2020

Review of clinical experience with digoxin immune Fab (ovine).

1 reference

12 December 2020

Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom

1 reference

12 December 2020

1 reference

12 December 2020

Neutralizacion de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente

1 reference

12 December 2020

Enzyme-linked immunosorbent assay for the detection of Bothrops jararaca venom

1 reference

12 December 2020

10.2165/00003088-200342080-00002

Identifiers

DOI

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Dimensions Publication ID

6 August 2017

1049565160

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