(Q34045996)

30 July 2017

title

The production of multi-transgenic pigs: update and perspectives for xenotransplantation (English)

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30 July 2017

Heiner Niemann

1

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30 July 2017

Bjoern Petersen

series ordinal

2

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30 July 2017

publication date

28 January 2016

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30 July 2017

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30 July 2017

volume

25

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30 July 2017

issue

3

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30 July 2017

page(s)

361-374

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siRNA mediated knockdown of tissue factor expression in pigs for xenotransplantation.

30 July 2017

cites work

1 reference

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21 January 2018

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Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation

21 January 2018

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Identification of new carbohydrate and membrane protein antigens in cardiac xenotransplantation

21 January 2018

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Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

21 January 2018

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Efficient TALEN-mediated gene knockout in livestock

21 January 2018

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A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence

21 January 2018

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Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

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Progress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literature

21 January 2018

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Intravascular thrombosis in discordant xenotransplantation.

21 January 2018

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Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs

21 January 2018

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Xenotransplantation: the next generation of engineered animals

21 January 2018

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T-cell responses during pig-to-primate xenotransplantation.

21 January 2018

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Suppression of human macrophage-mediated cytotoxicity by transgenic swine endothelial cell expression of HLA-G.

21 January 2018

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Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

21 January 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

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Cloning of the transgenic pigs expressing human decay accelerating factor and N-acetylglucosaminyltransferase III.

21 January 2018

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Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome

21 January 2018

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Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction

21 January 2018

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21 January 2018

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One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

21 January 2018

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Meta-analysis of the independent and cumulative effects of multiple genetic modifications on pig lung xenograft performance during ex vivo perfusion with human blood

21 January 2018

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Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

21 January 2018

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Gender non-specific efficacy of ZFN mediated gene targeting in pigs

21 January 2018

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Gene knockout and knockin by zinc-finger nucleases: current status and perspectives

21 January 2018

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Human NK cells can lyse porcine endothelial cells independent of their expression of Galalpha(1,3)-Gal and killing is enhanced by activation of either effector or target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Antibody- and complement-independent phagocytotic and cytolytic activities of human macrophages toward porcine cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Human natural killer lymphocytes directly recognize evolutionarily conserved oligosaccharide ligands expressed by xenogeneic tissues

21 January 2018

1 reference

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The role of platelets in coagulation dysfunction in xenotransplantation, and therapeutic options.

21 January 2018

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Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors.

21 January 2018

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Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

21 January 2018

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Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice

21 January 2018

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Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

21 January 2018

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Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Recombinant pig TFPI efficiently regulates human tissue factor pathways

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Increased human tumor necrosis factor-α levels induce procoagulant change in porcine endothelial cells in vitro.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells

21 January 2018

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Tissue factor knockdown in porcine islets: an effective approach to suppressing the instant blood-mediated inflammatory reaction

21 January 2018

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A TALE nuclease architecture for efficient genome editing

21 January 2018

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Are N-glycolylneuraminic acid (Hanganutziu-Deicher) antigens important in pig-to-human xenotransplantation?

21 January 2018

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Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis

21 January 2018

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Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation

21 January 2018

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Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease

21 January 2018

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Low levels of tissue factor are compatible with development and hemostasis in mice.

21 January 2018

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Molecular scissors and their application in genetically modified farm animals

21 January 2018

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The perspectives for porcine-to-human xenografts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Production of alpha 1,3-galactosyltransferase-deficient pigs

21 January 2018

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Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease

21 January 2018

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Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Carbon monoxide: present and future indications for a medical gas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Potential deleterious role of anti-Neu5Gc antibodies in xenotransplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Reduced nicotinamide-adenine dinucleotide phosphate dependent biliverdin reductase: partial purification and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Genome editing with engineered zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Transgenic swine: expression of human CD39 protects against myocardial injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Xenotransplantation: current status and a perspective on the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

21 January 2018

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One-step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering

21 January 2018

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The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11248-016-9934-8

Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice

21 January 2018

1 reference

12 December 2020

Endothelial cell protection and complement inhibition in xenotransplantation: a novel in vitro model using whole blood

1 reference

12 December 2020

Transgenic expression of the human A20 gene in cloned pigs provides protection against apoptotic and inflammatory stimuli

1 reference

12 December 2020

Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase

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12 December 2020

Tissue factor expression during human and mouse development

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12 December 2020

Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI

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12 December 2020

Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody

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12 December 2020

A20 zinc finger protein inhibits TNF and IL-1 signaling

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12 December 2020

Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment

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12 December 2020

Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys

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12 December 2020

Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience

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12 December 2020

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation

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12 December 2020

Live pigs produced from genome edited zygotes

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12 December 2020

Ferritin: a cytoprotective antioxidant strategem of endothelium

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12 December 2020

Pigs transgenic for human thrombomodulin have elevated production of activated protein C

1 reference

12 December 2020

Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons

1 reference

12 December 2020

Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: a major obstacle for xenotransplantation in humans

1 reference

12 December 2020

Targeted disruption of the murine tissue factor gene results in embryonic lethality

1 reference

12 December 2020

10.1007/S11248-016-9934-8

Identifiers

DOI

1 reference

release_3xv2yqfht5hsvmi4angqqpupty

30 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/3xv2yqfht5hsvmi4angqqpupty

24 November 2022

mapped directly with Wikidata item

1 reference