(Q34048070)

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Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

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Europe PubMed Central

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3 February 2020

Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration (English)

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3 February 2020

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Silvie Foldynová-Trantírková

1

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3 February 2020

Wulf Blankenfeldt

6

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3 February 2020

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3 February 2020

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3 February 2020

Lukáš Trantírek

10

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3 February 2020

Vítězslav Bryja

11

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3 February 2020

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Alois Kozubík

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3 February 2020

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Petra Sekyrová

2

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3 February 2020

Katerina Tmejová

3

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3 February 2020

Eva Brumovská

4

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3 February 2020

Ondrej Bernatík

5

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3 February 2020

publication date

27 May 2010

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3 February 2020

Breast Cancer Research

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3 February 2020

12

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3 February 2020

3

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3 February 2020

R30

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3 February 2020

describes a project that uses

object named as

RTCA

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

https://scigraph.springernature.com/pub.10.1186/bcr2581

0 references

Protein structure prediction on the Web: a case study using the Phyre server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

The selectivity of protein kinase inhibitors: a further update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

A versatile ligation-independent cloning method suitable for high-throughput expression screening applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

CUPSAT: prediction of protein stability upon point mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Structural evolution of the protein kinase-like superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Cadherins and catenins in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Molecular requirements for epithelial-mesenchymal transition during tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

The casein kinase 1 family: participation in multiple cellular processes in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

CD-Search: protein domain annotations on the fly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Casein kinase Iepsilon modulates the signaling specificities of dishevelled

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Regulation of casein kinase I epsilon activity by Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

The role of NFAT transcription factors in integrin-mediated carcinoma invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Crystal structure of a conformation-selective casein kinase-1 inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Immunophenotypic and prognostic analysis of E-cadherin and beta-catenin expression during breast carcinogenesis and tumour progression: a comparative study with CD44.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Wnt5a cloning, expression, and up-regulation in human primary breast cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Characterization of estrogen responsive transforming activity in human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

5 July 2018

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

Casein kinase I transduces Wnt signals

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

The casein kinase I family in Wnt signaling

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility

1 reference

https://api.crossref.org/works/10.1186%2FBCR2581

21 January 2018

Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917022

28 October 2018

c-met tyrosine kinase receptor expression is associated with abnormal beta-catenin expression and favourable prognostic factors in invasive breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20507565

12 December 2020

based on heuristic

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10.1186/BCR2581

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507565%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507565%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507565%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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