(Q34049942)

English

The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor (English)

1 reference

Europe PubMed Central

30 July 2017

author name string

Meilin Zhang

1

1 reference

Europe PubMed Central

30 July 2017

Dario Mizrachi

2

1 reference

Europe PubMed Central

30 July 2017

Francesca Fanelli

3

1 reference

Europe PubMed Central

30 July 2017

Deborah L Segaloff

4

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

20 May 2005

1 reference

Europe PubMed Central

30 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

30 July 2017

280

1 reference

Europe PubMed Central

30 July 2017

28

1 reference

Europe PubMed Central

30 July 2017

26169-26176

1 reference

Europe PubMed Central

30 July 2017

Structure of human follicle-stimulating hormone in complex with its receptor

1 reference

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28 July 2018

Insight into mutation-induced activation of the luteinizing hormone receptor: molecular simulations predict the functional behavior of engineered mutants at M398.

1 reference

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28 July 2018

A molecular dissection of the glycoprotein hormone receptors.

1 reference

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

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28 July 2018

Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Chimeras of the rat and human FSH receptors (FSHRs) identify residues that permit or suppress transmembrane 6 mutation-induced constitutive activation of the FSHR via rearrangements of hydrophobic interactions between helices 6 and 7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Efficacy at G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

1 reference

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Pleiotropic effects of substitutions of a highly conserved leucine in transmembrane helix III of the human lutropin/choriogonadotropin receptor with respect to constitutive activation and hormone responsiveness.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Gonadotropin-independent precocious puberty due to luteinizing hormone receptor mutations in Brazilian boys: a novel constitutively activating mutation in the first transmembrane helix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

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Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

A unique constitutively activating mutation in third transmembrane helix of luteinizing hormone receptor causes sporadic male gonadotropin-independent precocious puberty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

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An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

A model of the lutropin/choriogonadotropin receptor: insights into the structural and functional effects of constitutively activating mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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28 July 2018

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237128

28 July 2018

Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells

1 reference

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28 July 2018

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502102200

21 January 2018

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502102200

21 January 2018

Desensitization of Gs-coupled receptor signaling by constitutively active mutants of the human lutropin/choriogonadotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15908694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theoretical study on mutation-induced activation of the luteinizing hormone receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15908694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for constitutive lutropin receptor activation based on molecular simulation and engineered mutations in transmembrane helices 6 and 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/15908694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lutropin/choriogonadotropin receptor, a 2002 perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/15908694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M502102200

1 reference

Europe PubMed Central

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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