(Q34050694)

30 July 2017

1 reference

title

HIV-1 integrase inhibitors: past, present, and future (English)

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30 July 2017

Neamati N

1

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30 July 2017

Marchand C

series ordinal

2

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30 July 2017

Pommier Y

series ordinal

3

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30 July 2017

publication date

1 January 2000

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30 July 2017

published in

Advances in Pharmacology

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30 July 2017

volume

49

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30 July 2017

page(s)

147-165

1 reference

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

30 July 2017

cites work

1 reference

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7 January 2021

Molecular mechanisms in retrovirus DNA integration

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7 January 2021

Inhibition of human immunodeficiency virus type 1 integrase by the Fab fragment of a specific monoclonal antibody suggests that different multimerization states are required for different enzymatic functions

1 reference

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7 January 2021

Monoclonal antibodies against HIV type 1 integrase: clues to molecular structure

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7 January 2021

PMTI, a broadly active unusual single-stranded polyribonucleotide, inhibits human immunodeficiency virus replication by multiple mechanisms

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7 January 2021

The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of the in vitro integration of Moloney murine leukemia virus DNA by the DNA minor groove binder netropsin

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7 January 2021

Mode of interaction of G-quartets with the integrase of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Differential Alteration of the Anti-HIV-1 Effect of Phosphorothioate Oligonucleotide S-dC28 by AZT, Interferon-Alpha, and Dextran Sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

In vitro assays for activities of retroviral integrase

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https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Target site selection in transposition

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

A rapid in vitro assay for HIV DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Synthesis and anti-human immunodeficiency virus type 1 integrase activity of hydroxybenzoic and hydroxycinnamic acid flavon-3-yl esters

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

(-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Development of an acid-soluble assay for measuring retrovirus integrase 3'-OH terminal nuclease activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

HIV-1: fifteen proteins and an RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Recent advances in understanding V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

A 32,000-Dalton nucleic acid-binding protein from avian retravirus cores possesses DNA endonuclease activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Retroviral cDNA integration: mechanism, applications and inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Requirement of the avian retrovirus pp32 DNA binding protein domain for replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Biologically active oligodeoxyribonucleotides. 5. 5'-End-substituted d(TGGGAG) possesses anti-human immunodeficiency virus type 1 activity by forming a G-quadruplex structure

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The retroviral enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Nonspecific alcoholysis, a novel endonuclease activity of human immunodeficiency virus type 1 and other retroviral integrases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Structure-activity relationships: analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of replication of HIV-1 at both early and late stages of the viral life cycle by single-chain antibody against viral integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of human immunodeficiency virus integrase by bis-catechols

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The origins of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Chicoric acid analogues as HIV-1 integrase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Solution structure of the DNA binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Conformational aspects of HIV-1 integrase inhibition by a peptide derived from the enzyme central domain and by antibodies raised against this peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Effects of Tyrphostins, Protein Kinase Inhibitors, on Human Immunodeficiency Virus Type 1 Integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: the phenanthroline-cuprous complex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Mechanism of bacteriophage mu transposition

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

A new method for determining the stereochemistry of DNA cleavage reactions: application to the SfiI and HpaII restriction endonucleases and to the MuA transposase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Salicylhydrazine-containing inhibitors of HIV-1 integrase: implication for a selective chelation in the integrase active site

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Potent inhibitors of human immunodeficiency virus type 1 integrase: identification of a novel four-point pharmacophore and tetracyclines as novel inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The metal ion-induced cooperative binding of HIV-1 integrase to DNA exhibits a marked preference for Mn(II) rather than Mg(II).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Displacement of viral DNA termini from stable HIV-1 integrase nucleoprotein complexes induced by secondary DNA-binding interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibitors of human immunodeficiency virus integrase.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Retroviral integrases and their cousins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Cell protein cross-linking by erbstatin and related compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

HIV integrase: a target for AIDS therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Biochemical Characterization of the HIV-1 Integrase 3‘-Processing Activity and Its Inhibition by Phosphorothioate Oligonucleotides†

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Anti-human immunodeficiency virus drug combination strategies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

The human immunodeficiency virus integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Identification and characterization of a temperature-sensitive mutant of human immunodeficiency virus type 1 by alanine scanning mutagenesis of the integrase gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Coumarin-based inhibitors of HIV integrase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

Irreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2949026-5

7 January 2021

10.1016/S1054-3589(00)49026-5

Identifiers

DOI

1 reference

30 July 2017

1 reference