(Q34057877)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

review article

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title

The suppressors of cytokine signaling (SOCS) proteins: important feedback inhibitors of cytokine action (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

C J Greenhalgh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 October 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

published in

Experimental Hematology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

1105-1112

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

Negative regulators of cytokine signal transduction

1 November 2019

cites work

1 reference

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7 January 2021

The CIS/JAB family: novel negative regulators of JAK signaling pathways

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Cloning and characterization of novel CIS family genes

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https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Twenty proteins containing a C-terminal SOCS box form five structural classes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

SWiP-1: novel SOCS box containing WD-protein regulated by signalling centres and by Shh during development

1 reference

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7 January 2021

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

1 reference

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7 January 2021

SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

1 reference

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7 January 2021

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

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7 January 2021

SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The role of SOCS-3 in leptin signaling and leptin resistance

1 reference

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7 January 2021

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Thrombopoietin induces an SH2-containing protein, CIS1, which binds to Mpl: involvement of the ubiquitin proteosome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

STAT5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 reference

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7 January 2021

SOCS3 is essential in the regulation of fetal liver erythropoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

Gigantism in mice lacking suppressor of cytokine signalling-2

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2800%2900525-7

7 January 2021

10.1016/S0301-472X(00)00525-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027828%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference