(Q34058200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants (English)

1 reference

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15 January 2020

1 reference

2

1 reference

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15 January 2020

Sulzhan Bali

8

1 reference

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15 January 2020

Paul K Potter

15

1 reference

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15 January 2020

author name string

Michael T Cheeseman

1

1 reference

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15 January 2020

Debbie Williams

3

1 reference

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15 January 2020

Tertius A Hough

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Paras Pathak

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Maria R Romero

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Helen Hilton

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Andrew Parker

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Lucie Vizor

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Tom Purnell

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Kate Vowell

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Sara Wells

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Mahmood F Bhutta

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Steve D M Brown

16

1 reference

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15 January 2020

publication date

20 October 2011

1 reference

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15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

e1002336

1 reference

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Creative Commons Attribution 4.0 International

15 January 2020

copyright license

start time

20 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Unraveling the genetics of otitis media: from mouse to human and back again

5 July 2018

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5 July 2018

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CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice

5 July 2018

1 reference

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Geldanamycin and its anti-cancer activities

5 July 2018

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High cytokine levels in perforated acute otitis media exudates containing live bacteria

5 July 2018

1 reference

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c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner

5 July 2018

1 reference

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TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media.

5 July 2018

1 reference

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Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

5 July 2018

1 reference

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The role of inflammatory mediators in the pathogenesis of otitis media and sequelae

5 July 2018

1 reference

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Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies

5 July 2018

1 reference

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HIF-1 in the inflammatory microenvironment

5 July 2018

1 reference

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Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases

5 July 2018

1 reference

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Role of complement in host defense against pneumococcal otitis media

5 July 2018

1 reference

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Myeloid differentiation primary response gene 88 is required for the resolution of otitis media

5 July 2018

1 reference

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Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation.

5 July 2018

1 reference

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

5 July 2018

1 reference

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Vascular permeability, vascular hyperpermeability and angiogenesis

5 July 2018

1 reference

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Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

5 July 2018

1 reference

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Hypoxia inducible factor (HIF) function in innate immunity and infection

5 July 2018

1 reference

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Regulation of hypoxia-inducible factors during inflammation

5 July 2018

1 reference

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Transgenic models to understand hypoxia-inducible factor function.

5 July 2018

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Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.

5 July 2018

1 reference

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HIF-1alpha and HIF-2alpha play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle

5 July 2018

1 reference

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Vascular endothelial growth factor and its relationship to inflammatory mediators

5 July 2018

1 reference

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Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements

5 July 2018

1 reference

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Toll-like receptor 2-dependent NF-kappaB activation is involved in nontypeable Haemophilus influenzae-induced monocyte chemotactic protein 1 up-regulation in the spiral ligament fibrocytes of the inner ear.

5 July 2018

1 reference

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Perinecrotic hypoxia contributes to ischemia/reperfusion-accelerated outgrowth of colorectal micrometastases

5 July 2018

1 reference

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VEGF/VEGFR signalling as a target for inhibiting angiogenesis

5 July 2018

1 reference

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A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse

5 July 2018

1 reference

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Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media

5 July 2018

1 reference

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Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study

5 July 2018

1 reference

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VEGF receptor signalling - in control of vascular function

5 July 2018

1 reference

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The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen

5 July 2018

1 reference

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The role of HIF-1alpha in myeloid cell inflammation

5 July 2018

1 reference

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Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Chronic and recurrent otitis media: a genome scan for susceptibility loci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Interrelations between the middle and inner ear in otitis media.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Differential Expression of Cytokine Genes and Inducible Nitric Oxide Synthase Induced by Opacity Phenotype Variants ofStreptococcus pneumoniaeduring Acute Otitis Media in the Rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Expression of vascular endothelial growth factor receptors in experimental otitis media in the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Expression of cytokine and chemokine genes by human middle ear epithelial cells induced by influenza A virus and Streptococcus pneumoniae opacity variants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

The aetiology of otitis media with effusion: a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Middle ear and auditory tube: middle ear clearance, gas exchange, and pressure regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation with dependence on the second zinc finger domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Auditory development in the mouse: structural maturation of the middle ear.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Gas composition of the normal and the ventilated middle ear cavity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Epidemiologic patterns in childhood hearing loss: a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Review of round window membrane permeability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Gas Tension and pH in Middle Ear Effusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Clinical practice guideline: Otitis media with effusion

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK787/ZK222584, causes significant anti-arthritic effects in models of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Effect of recombinant vascular endothelial growth factor on experimental otitis media with effusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

The genetic component of middle ear disease in the first 5 years of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Eosinophil chemoattractants in the middle ear of patients with eosinophilic otitis media

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Adenoids provide a microenvironment for the generation of CD4(+), CD45RO(+), L-selectin(-), CXCR4(+), CCR5(+) T lymphocytes, a lymphocyte phenotype found in the middle ear effusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Effect of paranasal sinusitis on the development of otitis media with effusion: influence of eustachian tube function and adenoid immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Increased TLR7 expression in the adenoids among children with otitis media with effusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Role of interleukin-10 and transforming growth factor beta 1 in otitis media with effusion.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197687

Expression of Vascular Endothelial Growth Factor in Otitis Media

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Inflammatory Cells in Mucoid Effusion of Secretory Otitis Media

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Poly(I:C) synergizes with Th2 cytokines to induce TARC/CCL17 in middle ear fibroblasts established from mucosa of otitis media with effusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Cytokine and Chemokine Induction Using Cell Wall Component and Toxin Derived from Gram-Positive Bacteria in the Rat Middle Ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Mucosal Expression of Genes Encoding Possible Upstream Regulators of Na+ Transport During Pneumococcal Otitis Media

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Cell Adhesion Molecules of Experimental Otitis Media in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

PO2Levels in Middle Ear Effusions and Middle Ear Mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002336

Expression of inflammatory mediators in the otitis media induced by Helicobacter pylori antigen in mice

21 January 2018

1 reference

12 December 2020

Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis

1 reference

12 December 2020

Homozygous deletion of the CYP21A-TNXA-RP2-C4B gene region conferring C4B deficiency associated with recurrent respiratory infections

1 reference

12 December 2020

The role of vascular endothelial growth factor in pediatric otitis media with effusion

1 reference

12 December 2020

PO2 levels in middle ear effusions and middle ear mucosa

1 reference

12 December 2020

Characterization of otitis media with effusion based on the ratio of albumin and immunoglobulin G concentrations in the effusion

1 reference

12 December 2020

Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media

1 reference

12 December 2020

Middle ear gas composition in pathologic conditions: mass spectrometry in otitis media with effusion and atelectasis

1 reference

12 December 2020

Mucin gene expression in human middle ear epithelium

1 reference

12 December 2020

Cytokine levels in groups of patients with different duration of chronic secretory otitis

1 reference

12 December 2020

Effect of interferon gamma and CD40 ligation on intracellular monocyte survival of nontypeableHaemophilus influenzae

1 reference

12 December 2020

The bacteriology and cytology of chronic otitis media with effusion

1 reference

12 December 2020

Gene expression profiles of early pneumococcal otitis media in the rat

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1002336

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028672%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference