(Q34061068)

30 July 2017

title

The ClpP N-terminus coordinates substrate access with protease active site reactivity (English)

1 reference

30 July 2017

Laura D Jennings

1

1 reference

30 July 2017

Jen Bohon

series ordinal

2

1 reference

30 July 2017

Mark R Chance

series ordinal

3

1 reference

30 July 2017

Stuart Licht

series ordinal

4

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30 July 2017

language of work or name

English

0 references

publication date

25 September 2008

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30 July 2017

number of pages

10

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inferred from page(s)

published in

Biochemistry

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30 July 2017

volume

47

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30 July 2017

issue

42

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30 July 2017

page(s)

11031-11040

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Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases

30 July 2017

cites work

1 reference

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Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry

5 July 2018

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Hydroxyl radical-mediated modification of proteins as probes for structural proteomics

5 July 2018

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Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease

5 July 2018

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ClpP: a distinctive family of cylindrical energy-dependent serine proteases

5 July 2018

1 reference

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The Beamline X28C of the Center for Synchrotron Biosciences: a national resource for biomolecular structure and dynamics experiments using synchrotron footprinting.

5 July 2018

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Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1

5 July 2018

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Radiolytic protein footprinting with mass spectrometry to probe the structure of macromolecular complexes.

5 July 2018

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The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.

5 July 2018

1 reference

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Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Allosteric regulation of chaperonins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Control of peptide product sizes by the energy-dependent protease ClpAP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Secondary reactions and strategies to improve quantitative protein footprinting.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Sculpting the proteome with AAA(+) proteases and disassembly machines.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Proteolysis in Bacterial Regulatory Circuits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystal Structure of ClpX Molecular Chaperone from Helicobacter pylori

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Serine protease mechanism and specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Hydroxyl radical probe of protein surfaces using synchrotron X-ray radiolysis and mass spectrometry.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

AAA+ superfamily ATPases: common structure--diverse function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

A gated channel into the proteasome core particle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

The structures of HsIU and the ATP-dependent protease HsIU-HsIV

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Regulatory subunits of energy-dependent proteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystal structure of heat shock locus V (HslV) from Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Structure of 20S proteasome from yeast at 2.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Activity and specificity of Escherichia coli ClpAP protease in cleaving model peptide substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Endopeptidase Clp: ATP-dependent Clp protease from Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Installation and testing of a focusing mirror at beamline X28C for high flux x-ray radiolysis of biological macromolecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Radiolytic modification and reactivity of amino acid residues serving as structural probes for protein footprinting

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Communication between ClpX and ClpP during substrate processing and degradation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Dynamics of substrate denaturation and translocation by the ClpXP degradation machine

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Processive degradation of proteins by the ATP-dependent Clp protease from Escherichia coli. Requirement for the multiple array of active sites in ClpP but not ATP hydrolysis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920337

Enzymatic and structural similarities between the Escherichia coli ATP-dependent proteases, ClpXP and ClpAP

28 October 2018

1 reference

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The apparent absence of an acylenzyme intermediate in the chymotrypsin-catalyzed hydrolysis of acetyl-L-tryosin hydroxamic acid

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12 December 2020

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Identifiers

DOI

10.1021/BI8010169

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30 July 2017

1 reference

30 July 2017

1 reference