(Q34061182)

30 July 2017

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title

Rapid assessment of drug metabolism in the drug discovery process (English)

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30 July 2017

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Bertrand M

1

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30 July 2017

Jackson P

series ordinal

2

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30 July 2017

Walther B

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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European Journal of Pharmaceutical Sciences

30 July 2017

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30 July 2017

11 Suppl 2

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30 July 2017

S61-72

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Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Development of Caco-2 cells expressing high levels of cDNA-derived cytochrome P4503A4.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Photometric microtiter assay of inorganic phosphate in the presence of acid-labile organic phosphates

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Long-term primary cultures of adult human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Development of quantitative structure-pharmacokinetic relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Physiologically based pharmacokinetic modeling of a homologous series of barbiturates in the rat: a sensitivity analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Comparison of four experimental techniques for studying drug absorption kinetics in the anesthetized rat in situ.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid phase extraction plate for the sample preparation.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

A systems approach to molecular structure, intermolecular recognition, and emergence-dissolvence in medicinal research

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2800%2900165-2

7 January 2021

10.1016/S0928-0987(00)00165-2

Identifiers

DOI

1 reference

30 July 2017

1 reference