(Q54588059)

1 June 2018

title

Development of Caco-2 cells expressing high levels of cDNA-derived cytochrome P4503A4. (English)

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1 June 2018

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C L Crespi

1

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1 June 2018

B W Penman

series ordinal

2

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1 June 2018

M Hu

series ordinal

3

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1 June 2018

publication date

1 November 1996

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1 June 2018

published in

Pharmaceutical Research

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1 June 2018

volume

13

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1 June 2018

page(s)

1635-1641

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1 June 2018

issue

11

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1 June 2018

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

cites work

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12 December 2020

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

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12 December 2020

Characterization of a human cell line expressing high levels of cDNA-derived CYP2D6.

1 reference

12 December 2020

Peptide transporter function and prolidase activities in Caco-2 cells: a lack of coordinated expression

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12 December 2020

Mechanism and kinetics of transcellular transport of a new beta-lactam antibiotic loracarbef across an intestinal epithelial membrane model system (Caco-2)

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12 December 2020

Expression of cytochrome P-450 3A in HT29-MTX cells and Caco-2 clone TC7

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12 December 2020

The Caco-2 cell monolayers as an intestinal metabolism model: metabolism of dipeptide Phe-Pro

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12 December 2020

Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients

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12 December 2020

Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

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12 December 2020

Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1.

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12 December 2020

Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation

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12 December 2020

Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver

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12 December 2020

Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation

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12 December 2020

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

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12 December 2020

In vitro methods for assessing human hepatic drug metabolism: their use in drug development

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12 December 2020

First-pass metabolism of cyclosporin by the gut

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12 December 2020

Development of a human lymphoblastoid cell line constitutively expressing human CYP1A1 cDNA: substrate specificity with model substrates and promutagens

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12 December 2020

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

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12 December 2020

Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies

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12 December 2020

CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells

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12 December 2020

Stable expression of human cytochrome P450IA2 cDNA in a human lymphoblastoid cell line: role of the enzyme in the metabolic activation of aflatoxin B1.

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12 December 2020

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

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12 December 2020

A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus

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12 December 2020

The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3.

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12 December 2020

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

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12 December 2020

Identifiers

DOI

10.1023/A:1016428304366

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1 June 2018

PubMed ID

8956327

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1 June 2018