(Q34063451)

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Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis.

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scholarly article

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3 February 2020

Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20506525%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

glomerulonephritis

1 reference

based on heuristic

inferred from title

Randy Quentin Cron

7

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3 February 2020

Timothy Beukelman

6

object named as

Timothy Beukelman

1 reference

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3 February 2020

author name string

Jay Mehta

1

1 reference

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3 February 2020

Anna Genin

2

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3 February 2020

Michael Brunner

3

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3 February 2020

Lisabeth V Scalzi

4

1 reference

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3 February 2020

Nilamadhab Mishra

5

1 reference

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3 February 2020

publication date

1 August 2010

1 reference

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3 February 2020

Arthritis and Rheumatism

1 reference

Europe PubMed Central

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3 February 2020

62

1 reference

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3 February 2020

8

1 reference

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3 February 2020

2499-2509

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20506525%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Effective treatment of young patients with pediatric-onset, long-standing lupus nephritis with tacrolimus given as a single daily dose: an open-label pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Transcriptional repression of interleukin-2 in human systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Early growth response-1 is required for CD154 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

The role of CD40-CD154 interactions in autoimmunity and the benefit of disrupting this pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Decreased CD154 expression by neonatal CD4+ T cells is due to limitations in both proximal and distal events of T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

CD154 transcriptional regulation in primary human CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

A T cell-specific enhancer of the human CD40 ligand gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

CD40-CD40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Distinct NFAT family proteins are involved in the nuclear NFAT-DNA binding complexes from human thymocyte subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

CD40-CD40 ligand interaction in autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Transcription factors of the NFAT family: regulation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Expression of NFAT-family proteins in normal human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

The CD40L promoter contains nuclear factor of activated T cells-binding motifs which require AP-1 binding for activation of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

5 July 2018

Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FART.27554

21 January 2018

A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

HIV-1, NFAT, and cyclosporin: immunosuppression for the immunosuppressed?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Regulation of the murine Nfatc1 gene by NFATc2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

CD40 ligand-activated human monocytes amplify glomerular inflammatory responses through soluble and cell-to-cell contact-dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Clinical efficacy of cyclosporin a neoral in the treatment of paediatric lupus nephritis with heavy proteinuria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Effects of cyclosporine in severe systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921031

28 October 2018

Transcriptional regulation of cytokine genes in nontransformed T cells. Apparent constitutive signals in run-on assays can be caused by repeat sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear run-on assay using biotin labeling, magnetic bead capture and analysis by fluorescence-based RT-PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective activity of ERK-1 and ERK-2 mitogen-activated protein kinases in peripheral blood T lymphocytes from patients with systemic lupus erythematosus: potential role of altered coupling of Ras guanine nucleotide exchange factor hSos to adapter p

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: expression of the NF of activated T cells in eosinophils: regulation by IL-4 and IL-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal NF-kappa B activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal intracellular distribution of NFAT1 in T lymphocytes from patients with systemic lupus erythematosus and characteristic clinical features

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD134 expression on CD4+ T cells is associated with nephritis and disease activity in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of low-dose cyclosporine A in the treatment of refractory proteinuria in childhood-onset lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NFATc1 autoregulation: a crucial step for cell-fate determination

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tacrolimus vs. clobetasol propionate in the treatment of facial cutaneous lupus erythematosus: a randomized, double-blind, bilateral comparison study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of NF-ATc2 differentially regulate CD154 and IL-2 genes in T cells from patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signaling in systemic lupus erythematosus lymphocytes and its therapeutic exploitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20506525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.27554

1 reference

Europe PubMed Central

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3 February 2020

1 reference

Europe PubMed Central

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3 February 2020

1 reference

Europe PubMed Central

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3 February 2020

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