(Q34073721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

review article

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title

New perspectives on the design of cytokines and growth factors (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Kallen KJ

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Grötzinger J

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 November 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

published in

Trends in Biotechnology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

18

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

455-461

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

Defining epitopes: It's not as easy as it seems

1 November 2019

cites work

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7 January 2021

Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor

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High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

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7 January 2021

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

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Binding in the growth hormone receptor complex

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Hematopoietic receptor complexes

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A hot spot of binding energy in a hormone-receptor interface

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7 January 2021

Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface

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7 January 2021

The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes

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7 January 2021

IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

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Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation.

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Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.

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7 January 2021

Rational design of a mouse granulocyte macrophage-colony-stimulating factor receptor antagonist

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7 January 2021

Small peptides as potent mimetics of the protein hormone erythropoietin

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Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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7 January 2021

Structural plasticity in a remodeled protein-protein interface

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7 January 2021

Convergent solutions to binding at a protein-protein interface

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7 January 2021

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7 January 2021

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

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7 January 2021

Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.

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7 January 2021

Inter-species chimeras of leukaemia inhibitory factor define a major human receptor-binding determinant

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7 January 2021

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

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7 January 2021

Identification of Single Amino Acid Residues of Human IL-6 Involved in Receptor Binding and Signal Initiation

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7 January 2021

The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor α-Chain Is Determined Primarily by the Immunoglobulin-like Domain

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7 January 2021

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

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7 January 2021

Neuropoietic cytokines in the hematopoietic fold

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7 January 2021

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7 January 2021

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

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7 January 2021

Sympathetic neurons can produce and respond to interleukin 6

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7 January 2021

Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors

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7 January 2021

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

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7 January 2021

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

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7 January 2021

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

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7 January 2021

A New Type of Cytokine Receptor Antagonist Directly Targeting gp130

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7 January 2021

Semirational design of a potent, artificial agonist of fibroblast growth factor receptors

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7 January 2021

Rapid evolution of a protein in vitro by DNA shuffling

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7 January 2021

DNA shuffling of a family of genes from diverse species accelerates directed evolution

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7 January 2021

Optimization of DNA shuffling for high fidelity recombination

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7 January 2021

Evolution of a cytokine using DNA family shuffling

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7 January 2021

Finding Cinderella's slipper--proteins that fit

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7 January 2021

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11058786%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference