(Q34074338)

English

Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.

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5 February 2020

Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta (English)

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5 February 2020

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inferred from title

phosphorylation

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4

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5 February 2020

10

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5 February 2020

Daniel Kirchhofer

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Daniel Kirchhofer

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5 February 2020

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Yaowu He

1

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5 February 2020

Andreas Wortmann

2

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5 February 2020

Les J Burke

3

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5 February 2020

Mark N Adams

5

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5 February 2020

Ibtissam Abdul-Jabbar

6

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5 February 2020

James P Quigley

7

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5 February 2020

Richard Leduc

8

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5 February 2020

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15 June 2010

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5 February 2020

Journal of Biological Chemistry

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5 February 2020

285

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5 February 2020

26162-26173

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5 February 2020

34

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5 February 2020

ISOLATION FROM BEEF PANCREAS OF CRYSTALLINE TRYPSINOGEN, TRYPSIN, A TRYPSIN INHIBITOR, AND AN INHIBITOR-TRYPSIN COMPOUND

1 reference

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Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis

1 reference

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Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

1 reference

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5 July 2018

Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

1 reference

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The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges

1 reference

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The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation.

1 reference

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Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers

1 reference

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CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma

1 reference

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Mutation G827R in matriptase causing autosomal recessive ichthyosis with hypotrichosis yields an inactive protease.

1 reference

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CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma

1 reference

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5 July 2018

Matriptase-dependent cell surface proteolysis in epithelial development and pathogenesis

1 reference

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Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway

1 reference

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5 July 2018

Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells

1 reference

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Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells

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Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture

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Identification of membrane-bound serine proteinase matriptase as processing enzyme of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/angiomodulin/mac25).

1 reference

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Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS.

1 reference

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Adhesion signaling by a novel mitotic substrate of src kinases

1 reference

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Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

The C2 domain of PKCdelta is a phosphotyrosine binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

CDCP1 identifies a broad spectrum of normal and malignant stem/progenitor cell subsets of hematopoietic and nonhematopoietic origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

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DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells

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Delineation of prognostic biomarkers in prostate cancer

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5 July 2018

Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

5 July 2018

Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924022

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1 reference

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Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

1 reference

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1 reference

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1 reference

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Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice

1 reference

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21 January 2018

A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1.

1 reference

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Hepsin promotes prostate cancer progression and metastasis

1 reference

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1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.096453

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20551327%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

1 reference

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5 February 2020

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