(Q34075626)

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The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors.

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16 January 2020

The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors (English)

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16 January 2020

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16 January 2020

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16 January 2020

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16 January 2020

Anthony Tak-Cheung Chan

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16 January 2020

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16 January 2020

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Sai Wah Tsao

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16 January 2020

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Fan Fong Poon

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16 January 2020

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Gopesh Srivastava

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Gopesh Srivastava

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Xing-sheng Shu

1

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16 January 2020

Hua Geng

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16 January 2020

Jianming Ying

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16 January 2020

Chunhong Ma

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16 January 2020

Yajun Wang

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16 January 2020

Ying Ying

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16 January 2020

Jun Yu

13

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16 January 2020

Shi Huang

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16 January 2020

Xian Wang

8

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16 January 2020

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8 November 2011

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16 January 2020

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16 January 2020

6

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16 January 2020

11

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16 January 2020

e27346

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16 January 2020

copyright license

Creative Commons Attribution 4.0 International

8 November 2011

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April 2022 Public Data File from Crossref

copyright status

0 references

Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.

1 reference

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Nuclear cyclin D1: an oncogenic driver in human cancer

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The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development

1 reference

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Promoter methylation of the Wnt/beta-catenin signaling antagonist Dkk-3 is associated with poor survival in gastric cancer

1 reference

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Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis

1 reference

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Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells

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5 July 2018

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation.

1 reference

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DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications

1 reference

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Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

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Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer

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5 July 2018

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

1 reference

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GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy

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5 July 2018

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

1 reference

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Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers.

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Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5

1 reference

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Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer

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Silencing of bidirectional promoters by DNA methylation in tumorigenesis

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Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1371/JOURNAL.PONE.0027346

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16 January 2020

2011PLoSO...627346S

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Europe PubMed Central

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16 January 2020

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Europe PubMed Central

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16 January 2020

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