(Q34076047)

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E2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex

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Europe PubMed Central

PubMed publication ID

30 July 2017

E2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

3

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Michael J. Matunis

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Alexander C Drohat

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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Christopher T Coey

1

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31 May 2020

Megan E Fitzgerald

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Katherine H Reiter

4

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31 May 2020

Catherine M Guzzo

5

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31 May 2020

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21 April 2014

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30 July 2017

Journal of Biological Chemistry

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31 May 2020

289

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31 May 2020

22

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31 May 2020

15810-15819

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Europe PubMed Central

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31 May 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4140935/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer

1 reference

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5 July 2018

Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.

1 reference

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5 July 2018

DNA-dependent SUMO modification of PARP-1

1 reference

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5 July 2018

Sumoylation: a regulatory protein modification in health and disease

1 reference

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5 July 2018

Retracted: SUMOylation of Mouse p53b by SUMO-1 Promotes Its Pro-Apoptotic Function in Ovarian Granulosa Cells

1 reference

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5 July 2018

Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming

1 reference

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5 July 2018

MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles

1 reference

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5 July 2018

Function and regulation of SUMO proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair

1 reference

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5 July 2018

Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

The discovery of 5-formylcytosine in embryonic stem cell DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Regulation of the p53 pathway by ubiquitin and related proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Principles of ubiquitin and SUMO modifications in DNA repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Performing in vitro sumoylation reactions using recombinant enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Purification of SUMO conjugating enzymes and kinetic analysis of substrate conjugation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Thymine-DNA glycosylase interacts with and functions as a coactivator of p53 family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Concepts in sumoylation: a decade on

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Crystal structure of SUMO-3-modified thymine-DNA glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Crystal structure of thymine DNA glycosylase conjugated to SUMO-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Protein modification by SUMO

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

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5 July 2018

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

https://pubmed.ncbi.nlm.nih.gov/24753249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140935

5 July 2018

Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Kinetics of the action of thymine DNA glycosylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Purification and activity assays for Ubc9, the ubiquitin-conjugating enzyme for the small ubiquitin-like modifier SUMO.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572081

21 January 2018

Identifiers

10.1074/JBC.M114.572081

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24753249%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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