(Q34079451)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

LOX-1 in atherosclerosis: biological functions and pharmacological modifiers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

5

Joel Moss

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Suowen Xu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Sayoko Ogura

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Jiawei Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Peiqing Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

publication date

3 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

17 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

2859-2872

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00018-012-1194-z

17 February 2020

exact match

0 references

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Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

5 July 2018

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Potential involvement of LOX-1 in functional consequences of endothelial senescence

5 July 2018

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Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer

5 July 2018

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Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis

5 July 2018

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CRP enhances soluble LOX-1 release from macrophages by activating TNF-α converting enzyme

5 July 2018

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5 July 2018

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Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells

5 July 2018

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OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

5 July 2018

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Effects of berberine on expression of LOX-1 and SR-BI in human macrophage-derived foam cells induced by ox-LDL

5 July 2018

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Calcium channel blocker (diltiazem) inhibits apoptosis of vascular smooth muscle cell exposed to high glucose concentration through lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) pathway.

5 July 2018

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Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE(-/-) mouse model.

5 July 2018

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Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells

5 July 2018

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5 July 2018

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SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

5 July 2018

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LOX index, a novel predictive biochemical marker for coronary heart disease and stroke.

5 July 2018

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Lox-1: the multifunctional receptor underlying cardiovascular dysfunction.

5 July 2018

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Palmitic acid enhances lectin-like oxidized LDL receptor (LOX-1) expression and promotes uptake of oxidized LDL in macrophage cells

5 July 2018

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LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

5 July 2018

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5 July 2018

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5 July 2018

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Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels

5 July 2018

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Lectin-like oxidized low-density lipoprotein receptor-1, a new promising target for the therapy of atherosclerosis?

5 July 2018

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Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling

5 July 2018

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Leukocyte recruitment in atherosclerosis: potential targets for therapeutic approaches?

5 July 2018

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Dominant-negative lox-1 blocks homodimerization of wild-type lox-1-induced cell proliferation through extracellular signal regulated kinase 1/2 activation

5 July 2018

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Molecular dissection of angiotensin II-activated human LOX-1 promoter

5 July 2018

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Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders

5 July 2018

1 reference

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Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis

5 July 2018

1 reference

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PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

5 July 2018

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Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells

5 July 2018

1 reference

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Regulation of glycosaminoglycan structure and atherogenesis.

5 July 2018

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Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation

5 July 2018

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Glucose enhances endothelial LOX-1 expression: role for LOX-1 in glucose-induced human monocyte adhesion to endothelium

5 July 2018

1 reference

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Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation

5 July 2018

1 reference

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LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis

5 July 2018

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Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in atherogenesis

5 July 2018

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The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide

5 July 2018

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Activation-dependent surface expression of LOX-1 in human platelets

5 July 2018

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Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells

5 July 2018

1 reference

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Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

5 July 2018

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Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB

5 July 2018

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Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells

5 July 2018

1 reference

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A platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1.

5 July 2018

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Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions

5 July 2018

1 reference

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Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation

5 July 2018

1 reference

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The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142049

Atherosclerosis — An Inflammatory Disease

5 July 2018

1 reference

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Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: upregulated expression by TNF-alpha

5 July 2018

1 reference

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Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene

5 July 2018

1 reference

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Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor

5 July 2018

1 reference

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An endothelial receptor for oxidized low-density lipoprotein

5 July 2018

1 reference

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Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

5 July 2018

1 reference

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Activation of lectin-like oxidized low-density lipoprotein receptor-1 induces apoptosis in cultured neonatal rat cardiac myocytes

5 July 2018

1 reference

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Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion

21 January 2018

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Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus

21 January 2018

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Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice

21 January 2018

1 reference

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Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet

21 January 2018

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Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis

21 January 2018

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Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells

21 January 2018

1 reference

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Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet.

21 January 2018

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LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells.

21 January 2018

1 reference

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Statins inhibit oxidized-LDL-mediated LOX-1 expression, uptake of oxidized-LDL and reduction in PKB phosphorylation

21 January 2018

1 reference

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Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells

21 January 2018

1 reference

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Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis

21 January 2018

1 reference

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Expression of lectin-like oxidized LDL receptor-1 in smooth muscle cells after vascular injury

21 January 2018

1 reference

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Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Apoptosis of vascular cells by oxidized LDL: involvement of caspases and LOX-1 and its implication in atherosclerotic plaque rupture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Oxidized LDL modulates Bax/Bcl-2 through the lectinlike Ox-LDL receptor-1 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Regulation of TGFbeta1-mediated collagen formation by LOX-1: studies based on forced overexpression of TGFbeta1 in wild-type and lox-1 knock-out mouse cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Ox-LDL-induced LOX-1 expression in vascular smooth muscle cells: role of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Oxidized-LDL through LOX-1 increases the expression of angiotensin converting enzyme in human coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Effect of advanced glycation end products on lectin-like oxidized low density lipoprotein receptor-1 expression in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in Watanabe heritable hyperlipidemic rabbits: a new pleiotropic effect of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Cardiac hypertrophy during hypercholesterolemia and its amelioration with rosuvastatin and amlodipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Nifedipine prevents apoptosis of endothelial cells induced by oxidized low-density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1194-Z

Aspirin and pravastatin reduce lectin-like oxidized low density lipoprotein receptor-1 expression, adhesion molecules and oxidative stress in human coronary artery endothelial cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142049

Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142049

Circulating Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 are Associated with Inflammatory Markers

28 October 2018

1 reference

12 December 2020

LOX-1 as a natural IFN- -mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells

1 reference

12 December 2020

Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts prognosis after acute coronary syndrome--a pilot study

1 reference

12 December 2020

Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome--comparison with other biomarkers

1 reference

12 December 2020

Associations of atherosclerotic risk factors with oxidized low-density lipoprotein evaluated by LOX-1 ligand activity in healthy men

1 reference

12 December 2020

Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in apolipoprotein-E knockout mice fed a high cholesterol diet

1 reference

12 December 2020

Identification of soluble forms of lectin-like oxidized LDL receptor-1

1 reference

12 December 2020

Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from use of antisense LOX-1 mRNA and chemical inhibitors

1 reference

12 December 2020

Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species

1 reference

12 December 2020

The platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells

1 reference

12 December 2020

Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system

1 reference

12 December 2020

Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis

1 reference

12 December 2020

Metformin reduces endothelial cell expression of both the receptor for advanced glycation end products and lectin-like oxidized receptor 1

1 reference

12 December 2020

Anti-LOX-1 rescues endothelial function in coronary arterioles in atherosclerotic ApoE knockout mice

1 reference

12 December 2020

10.1007/S00018-012-1194-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

23124189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124189%20AND%20SRC:MED&resulttype=core&format=json