(Q34080235)

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Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing.

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scholarly article

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13 March 2020

Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing (English)

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13 March 2020

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Frederik Dagnæs-Hansen

3

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13 March 2020

4

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13 March 2020

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13 March 2020

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13 March 2020

Robert A. Fenton

8

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13 March 2020

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13 March 2020

author name string

Shan Gao

1

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13 March 2020

San Hein

2

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13 March 2020

Erik I Christensen

7

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13 March 2020

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13 August 2014

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13 March 2020

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13 March 2020

4

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13 March 2020

10

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13 March 2020

1039-1051

1 reference

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13 March 2020

Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering

1 reference

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Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration

1 reference

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28 July 2018

Endocytic receptors in the renal proximal tubule.

1 reference

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28 July 2018

Cell biology of vasopressin-regulated aquaporin-2 trafficking.

1 reference

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Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane.

1 reference

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28 July 2018

In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important

1 reference

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New short interfering RNA-based therapies for glomerulonephritis

1 reference

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28 July 2018

Targeting kidney mesangium by nanoparticles of defined size

1 reference

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28 July 2018

Advances in using chitosan-based nanoparticles for in vitro and in vivo drug and gene delivery

1 reference

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28 July 2018

Drug targeting to the kidney: Advances in the active targeting of therapeutics to proximal tubular cells

1 reference

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28 July 2018

Application of siRNA in targeting protein expression in kidney disease

1 reference

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Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

1 reference

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28 July 2018

Paradoxical glomerular filtration of carbon nanotubes

1 reference

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Novel siRNA delivery system to target podocytes in vivo

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28 July 2018

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

1 reference

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28 July 2018

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

1 reference

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28 July 2018

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

1 reference

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28 July 2018

Specific renal uptake of randomly 50% N-acetylated low molecular weight chitosan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142293

28 July 2018

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model

1 reference

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28 July 2018

Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2.

1 reference

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28 July 2018

Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes

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Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles

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28 July 2018

Randomly 50% N-acetylated low molecular weight chitosan as a novel renal targeting carrier

1 reference

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28 July 2018

How does proteinuria cause progressive renal damage?

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28 July 2018

Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury.

1 reference

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28 July 2018

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

1 reference

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28 July 2018

Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.

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28 July 2018

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

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28 July 2018

Megalin/gp330 mediates uptake of albumin in renal proximal tubule

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28 July 2018

Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes

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28 July 2018

Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs

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28 July 2018

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28 October 2018

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

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Mouse model of proximal tubule endocytic dysfunction.

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28 October 2018

Enhanced accumulation of low-molecular-weight chitosan in kidneys: a study on the influence of N-acetylation of chitosan on the renal targeting.

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28 October 2018

Small interfering RNA targeting IKKβ prevents renal ischemia-reperfusion injury in rats.

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28 October 2018

Chemically modified siRNA prolonged RNA interference in renal disease

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28 October 2018

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28 October 2018

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28 October 2018

Long-term regulation of four renal aquaporins in rats.

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25157280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of chitosan as a biomaterial: studies on its safety and hemostatic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/25157280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.7150/THNO.7866

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Europe PubMed Central

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13 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157280%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157280%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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