(Q34081415)

30 July 2017

title

From nonpeptide toward noncarbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease (English)

1 reference

30 July 2017

author

Hans-Georg Kräusslich

13

Hans-Georg Kräusslich

1 reference

30 July 2017

Jochen Bodem

12

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Jan Konvalinka

Jan Konvalinka

15

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Vladimír Král

Vladimír Král

14

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Zbyszek Otwinowski

5

Zbyszek Otwinowski

1 reference

30 July 2017

Petr Cígler

1

1 reference

30 July 2017

Milan Kozísek

2

1 reference

30 July 2017

Pavlína Rezácová

3

1 reference

30 July 2017

Jírí Brynda

4

1 reference

30 July 2017

Jana Pokorná

6

1 reference

30 July 2017

Jaromír Plesek

7

1 reference

30 July 2017

Bohumír Grüner

8

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30 July 2017

Lucie Dolecková-Maresová

9

1 reference

30 July 2017

Martin Mása

10

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30 July 2017

Juraj Sedlácek

11

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30 July 2017

language of work or name

English

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publication date

14 October 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

43

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30 July 2017

page(s)

15394-15399

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Design of HIV-1 protease inhibitors active on multidrug-resistant virus

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Determining and overcoming resistance to HIV protease inhibitors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Fullerene derivatives: an attractive tool for biological applications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

The Chemistry of Neutron Capture Therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Production of TNFalpha and IL-6 by activated whole blood from HIV-1 infected patients detected by a one-stage procedure: relationship with the phenotype of HIV-1 isolates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Domain flexibility in retroviral proteases: structural implications for drug resistant mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Principles of protein-protein interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic properties.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Active human immunodeficiency virus protease is required for viral infectivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Specific inhibition of HIV-1 protease by boronated porphyrins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

17 The kinetics of reversible tight-binding inhibition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1255736

Applications of Radiolabeled Boron Clusters to the Diagnosis and Treatment of Cancer

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

A new class of androgen receptor antagonists bearing carborane in place of a steroidal skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

Carboranes: A New Class of Weakly Coordinating Anions for Strong Electrophiles, Oxidants, and Superacids

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

The murine endogenous retrovirus MIA14 encodes an active aspartic proteinase that is functionally similar to proteinases from D-type retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507577102

Protein kinase C modulators bearing dicarba-CLOSO-dodecaborane as a hydrophobic pharmacophore

21 January 2018

1 reference

12 December 2020

Modulators of tumor necrosis factor alpha production bearing dicarba-closo-dodecaborane as a hydrophobic pharmacophore

1 reference

12 December 2020

1 reference

12 December 2020

Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex

1 reference

12 December 2020

Primary structure of cathepsin D inhibitor from potatoes and its structure relationship to soybean trypsin inhibitor family

1 reference

12 December 2020

Separation of human pepsin and gastricsin by affinity chromatography with an immobilized synthetic inhibitor

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0507577102

1 reference

30 July 2017

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1 reference

30 July 2017

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