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Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway.
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stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
viral mRNA export from host cell nucleus
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0046784
virus
0 references
author
Elisa Izaurralde
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Iain William Mattaj
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Stuart A Wilson
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
M D Koffa
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
J B Clements
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
S Wadd
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
S Kuersten
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
language of work or name
English
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publication date
1 October 2001
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
20
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
20
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
5769-5778
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
cites work
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpes simplex virus 1 ICP27 is required for transcription of two viral late (gamma 2) genes in infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Processing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Epstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The multifunctional herpes simplex virus IE63 protein interacts with heterogeneous ribonucleoprotein K and with casein kinase 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Association with the cellular export receptor CRM 1 mediates function and intracellular localization of Epstein-Barr virus SM protein, a regulator of gene expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Identification of a nuclear export receptor for tRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The herpes simplex virus immediate-early protein ICP27 shuttles between nucleus and cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpes simplex virus type 1 immediate early protein IE63 shuttles between nuclear compartments and the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
CRM1 is an export receptor for leucine-rich nuclear export signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Regulation of herpes simplex virus poly (A) site usage and the action of immediate-early protein IE63 in the early-late switch.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The herpes simplex virus type 1 regulatory protein ICP27 coimmunoprecipitates with anti-Sm antiserum, and the C terminus appears to be required for this interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Association of individual hnRNP proteins and snRNPs with nascent transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
hnRNP proteins and the biogenesis of mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
A nuclear cap binding protein complex involved in pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Identification of a signal for rapid export of proteins from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Nuclear export of different classes of RNA is mediated by specific factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Mutational analysis of the herpes simplex virus type 1 trans-inducing factor Vmw65.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
5 July 2018
Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
28 October 2018
The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
28 October 2018
Immediate early protein IE63 of herpes simplex virus type 1 binds RNA directly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
28 October 2018
Herpes simplex virus induces a processing factor that stimulates poly(A) site usage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125682
retrieved
28 October 2018
Identifiers
DOI
10.1093/EMBOJ/20.20.5769
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PMC publication ID
125682
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed publication ID
11598019
1 reference
stated in
Europe PubMed Central
PMC publication ID
125682
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
ResearchGate publication ID
11752157
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