(Q34085091)

30 July 2017

title

Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant (English)

1 reference

30 July 2017

0 references

1 reference

2

Eviatar Nevo

1 reference

30 July 2017

Nicola J Nasser

1

1 reference

30 July 2017

Itay Shafat

3

1 reference

30 July 2017

Neta Ilan

4

1 reference

30 July 2017

Israel Vlodavsky

5

1 reference

30 July 2017

Aaron Avivi

6

1 reference

30 July 2017

language of work or name

English

0 references

publication date

4 October 2005

1 reference

30 July 2017

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

30 July 2017

volume

102

1 reference

30 July 2017

issue

42

1 reference

30 July 2017

page(s)

15161-15166

1 reference

Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

p53--a key player in tumoral and evolutionary adaptation: a lesson from the Israeli blind subterranean mole rat.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

How did alternative splicing evolve?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Processing and activation of latent heparanase occurs in lysosomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Heparanase affects adhesive and tumorigenic potential of human glioma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Alternative splicing and evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Secretion of Heparanase Protein Is Regulated by Glycosylation in Human Tumor Cell Lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Heterodimer formation is essential for heparanase enzymatic activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Circadian genes in a blind subterranean mammal II: conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspecies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Heparanase: a key enzyme involved in cell invasion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Genomic organization and chromosome localization of the newly identified human heparanase gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Functions of cell surface heparan sulfate proteoglycans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Human heparanase. Purification, characterization, cloning, and expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Cloning and functional expression of a human heparanase gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Matrix proteoglycans: from molecular design to cellular function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Working underground: respiratory adaptations in the blind mole rat

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Morphometric model for pulmonary diffusing capacity. I. Membrane diffusing capacity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Evidence for improved myocardial oxygen delivery and function during hypoxia in the mole rat.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

The eye of the blind mole rat, Spalax ehrenbergi. Rudiment with hidden function?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Proteoglycans: structures and interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Site-directed mutagenesis, proteolytic cleavage, and activation of human proheparanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Adaptive hypoxic tolerance in the subterranean mole rat Spalax ehrenbergi: the role of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Increased blood vessel density provides the mole rat physiological tolerance to its hypoxic subterranean habitat

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Cloning, expression, and purification of mouse heparanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Biological clock in total darkness: the Clock/MOP3 circadian system of the blind subterranean mole rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507279102

Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1257723

Constitutive upregulation of hypoxia-inducible factor-1alpha mRNA occurring in highly metastatic lung carcinoma cells leads to vascular endothelial growth factor overexpression upon hypoxic exposure

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16204381

12 December 2020

inferred from PubMed ID database lookup

Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16204381

12 December 2020

inferred from PubMed ID database lookup

Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16204381

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0507279102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference