(Q34085184)

30 July 2017

title

Adipose differentiation-related protein regulates lipids and insulin in pancreatic islets (English)

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30 July 2017

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D M Faleck

1

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30 July 2017

K Ali

2

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30 July 2017

R Roat

3

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30 July 2017

M J Graham

4

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30 July 2017

R M Crooke

5

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30 July 2017

R Battisti

6

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30 July 2017

E Garcia

7

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30 July 2017

R S Ahima

8

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30 July 2017

Y Imai

9

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30 July 2017

publication date

18 May 2010

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American Journal of Physiology - Endocrinology and Metabolism

30 July 2017

published in

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30 July 2017

volume

299

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30 July 2017

issue

2

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30 July 2017

page(s)

E249-57

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Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice

30 July 2017

cites work

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5 July 2018

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Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the beta-cell line INS-1

5 July 2018

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12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

5 July 2018

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5 July 2018

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5 July 2018

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Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.

5 July 2018

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Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnover

5 July 2018

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Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice

5 July 2018

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Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide.

5 July 2018

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GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

5 July 2018

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Regulation of Triglyceride Metabolism. III. Emerging role of lipid droplet protein ADFP in health and disease

5 July 2018

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5 July 2018

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5 July 2018

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OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

5 July 2018

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5 July 2018

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Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins

5 July 2018

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Lipid droplets: a unified view of a dynamic organelle

5 July 2018

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PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver

5 July 2018

1 reference

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Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein

5 July 2018

1 reference

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Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet.

5 July 2018

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Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin.

5 July 2018

1 reference

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ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells

5 July 2018

1 reference

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Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Role of PAT proteins in lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

S3-12, Adipophilin, and TIP47 package lipid in adipocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Fatty acid metabolism and insulin secretion in pancreatic beta cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

A simple method for the isolation and purification of total lipides from animal tissues

5 July 2018

1 reference

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Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome

5 July 2018

1 reference

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

5 July 2018

1 reference

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Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001

5 July 2018

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Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

5 July 2018

1 reference

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Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Mechanisms of lipid-body formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Triacsin C blocks de novo synthesis of glycerolipids and cholesterol esters but not recycling of fatty acid into phospholipid: evidence for functionally separate pools of acyl-CoA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Oleic acid-induced ADRP expression requires both AP-1 and PPAR response elements, and is reduced by Pycnogenol through mRNA degradation in NMuLi liver cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Fasting in healthy subjects is associated with intrahepatic accumulation of lipids as assessed by 1H-magnetic resonance spectroscopy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Inhibition of PKCepsilon improves glucose-stimulated insulin secretion and reduces insulin clearance.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Starvation-induced changes of palmitate metabolism and insulin secretion in isolated rat islets stimulated by glucose

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928510

Severe steatosis resulted from anorexia nervosa leading to fatal hepatic failure

28 October 2018

1 reference

12 December 2020

An improved method for isolation of mouse pancreatic islets

1 reference

12 December 2020

A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation

1 reference

12 December 2020

Inhibitory effects of fatty acids on glucose-regulated B-cell function: association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism

1 reference

12 December 2020

Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro

1 reference

12 December 2020

10.1152/AJPENDO.00646.2009

Identifiers

DOI

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30 July 2017

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30 July 2017

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