(Q34088201)

30 July 2017

Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome (English)

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30 July 2017

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5

Gary Lynch

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30 July 2017

6

Christine M Gall

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30 July 2017

Lulu Y Chen

1

1 reference

30 July 2017

Christopher S Rex

2

1 reference

30 July 2017

Alex H Babayan

3

1 reference

30 July 2017

Eniko A Kramár

4

1 reference

30 July 2017

Julie C Lauterborn

7

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30 July 2017

language of work or name

English

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publication date

1 August 2010

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30 July 2017

Journal of Neuroscience

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30 July 2017

30

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30 July 2017

33

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30 July 2017

10977-10984

1 reference

describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2929244/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Fragile x mental retardation 1 and filamin a interact genetically in Drosophila long-term memory

5 July 2018

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Structural dynamics of dendritic spines in memory and cognition

5 July 2018

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ADF/cofilin: a functional node in cell biology

5 July 2018

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Actin, a central player in cell shape and movement

5 July 2018

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Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity

5 July 2018

1 reference

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Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation

5 July 2018

1 reference

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Local protein synthesis, actin dynamics, and LTP consolidation

5 July 2018

1 reference

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Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome

5 July 2018

1 reference

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The substrates of memory: defects, treatments, and enhancement

5 July 2018

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Rho-linked genes and neurological disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Integrin-driven actin polymerization consolidates long-term potentiation

5 July 2018

1 reference

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Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.

5 July 2018

1 reference

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Essential role of CIB1 in regulating PAK1 activation and cell migration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

The actin cytoskeleton: integrating form and function at the synapse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Regulation of actin dynamics by WASP and WAVE family proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

BDNF induces translocation of initiation factor 4E to mRNA granules: Evidence for a role of synaptic microfilaments and integrins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Biology of the p21-activated kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Integration of signals to the Arp2/3 complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Identification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Dynamic actin filaments are required for stable long-term potentiation (LTP) in area CA1 of the hippocampus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Control of actin dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Reversal of LTP by theta frequency stimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Adult fragile X syndrome. Clinico-neuropathologic findings.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Inhibition of actin polymerization by latrunculin A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

The Fra(X) syndrome: neurological, electrophysiological, and neuropathological abnormalities.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Brain-derived neurotrophic factor rescues synaptic plasticity in a mouse model of fragile X syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Changes in synaptic morphology accompany actin signaling during LTP.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Phosphorylation of cortactin by p21-activated kinase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Theta stimulation polymerizes actin in dendritic spines of hippocampus.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

From fragile X mental retardation protein to Rac1 GTPase: new insights from Fly CYFIP.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929244

Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va

28 October 2018

1 reference

12 December 2020

Dendritic Spine Pathology: Cause or Consequence of Neurological Disorders?

1 reference

12 December 2020

Spatial organization of cofilin in dendritic spines

1 reference

12 December 2020

Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements

1 reference

12 December 2020

10.1523/JNEUROSCI.1077-10.2010

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference