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Use of the nuclear receptor PXR to predict drug interactions
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Use of the nuclear receptor PXR to predict drug interactions
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
author name string
Moore JT
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
Kliewer SA
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
language of work or name
English
0 references
publication date
1 November 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Toxicology
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
volume
153
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
page(s)
1-10
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
issue
1-3
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
cites work
Steroid hormone receptors: many actors in search of a plot
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
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inferred from DOI database lookup
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SXR, a novel steroid and xenobiotic-sensing nuclear receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Newer diagnostic techniques and problems in Cushing's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a new class of steroid hormone receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Orphan nuclear receptors: from gene to function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome P-450 3A4: regulation and role in drug metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate specificities and functions of the P450 cytochromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Orphan nuclear receptors: shifting endocrinology into reverse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RXR heterodimers and orphan receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P450 genes: structure, evolution, and regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of pregnenolone-16 -carbonitrile on hepatic mixed-function oxygenases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of human hepatocytes to study P450 gene induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Counting the costs of drug-related adverse events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-483X%2800%2900300-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0300-483X(00)00300-0
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
Fatcat ID
release_qtyldjzjwfcbzhgae7klwbz7qy
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/qtyldjzjwfcbzhgae7klwbz7qy
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
11090943
1 reference
stated in
Europe PubMed Central
PubMed ID
11090943
retrieved
30 July 2017
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