(Q34093031)

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Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Justin E Elenewski

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Justin Elenewski

2

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Carmen Abate

1

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Amalia Azzariti

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Amalia Azzariti

6

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Mauro Niso

3

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Roberto Perrone

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Roberto Perrone

7

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author name string

Francesco Berardi

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Nicola Antonio Colabufo

5

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Europe PubMed Central

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31 July 2017

Richard A Glennon

8

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Europe PubMed Central

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31 July 2017

publication date

1 February 2010

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

5

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Europe PubMed Central

PubMed publication ID

31 July 2017

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

268-273

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Europe PubMed Central

PubMed publication ID

31 July 2017

1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review

1 reference

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21 January 2018

A structure-affinity and comparative molecular field analysis of sigma-2 (sigma2) receptor ligands

1 reference

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Dialysis or diffusion?

1 reference

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Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

1 reference

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Sigma-1 receptor knockout mice display a depressive-like phenotype.

1 reference

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Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice

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Purification, molecular cloning, and expression of the mammalian sigma1-binding site

1 reference

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7 January 2021

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The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator

1 reference

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Sigma-2 receptors as a biomarker of proliferation in solid tumours

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Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.

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4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity

1 reference

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Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines

1 reference

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A new method for evaluating sigma(2) ligand activity in the isolated guinea-pig bladder

1 reference

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Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer.

1 reference

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Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity

1 reference

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Is the sigma2 receptor a histone binding protein?

1 reference

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Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization

1 reference

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7 January 2021

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A charged and contoured surface on the nucleosome regulates chromatin compaction

1 reference

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7 January 2021

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Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly

1 reference

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7 January 2021

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Histone octamer function in vivo: mutations in the dimer-tetramer interfaces disrupt both gene activation and repression

1 reference

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The effect of salts on the stability of the H2A-H2B histone dimer

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Comparative protein modelling by satisfaction of spatial restraints

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Automatic atom type and bond type perception in molecular mechanical calculations

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Scalable molecular dynamics with NAMD

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PROCHECK: a program to check the stereochemical quality of protein structures

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Statistical potential for assessment and prediction of protein structures

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MOPAC: a semiempirical molecular orbital program

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Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

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A semiempirical free energy force field with charge-based desolvation

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Development and testing of a general amber force field

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

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The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation

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The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

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Identifiers

10.1002/CMDC.200900402

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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