(Q34094582)

31 July 2017

Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability (English)

1 reference

31 July 2017

4

Eva-Maria Mandelkow

0 references

Daniel Jobst Muller

object named as

Daniel J Muller

6

0 references

Eckhard Mandelkow

5

object named as

Eckhard Mandelkow

1 reference

31 July 2017

Susanne Wegmann

1

1 reference

31 July 2017

Yu Jin Jung

2

1 reference

31 July 2017

Subashchandrabose Chinnathambi

3

1 reference

31 July 2017

language of work or name

English

0 references

publication date

21 June 2010

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

285

1 reference

31 July 2017

27302-27313

1 reference

31 July 2017

35

1 reference

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2930729/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Prion-like transmission of protein aggregates in neurodegenerative diseases

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Prion-like propagation of cytosolic protein aggregates: insights from cell culture models

5 July 2018

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Protein aggregation: more than just fibrils

5 July 2018

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Structural polymorphism of Alzheimer Abeta and other amyloid fibrils

5 July 2018

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Propagation of tau misfolding from the outside to the inside of a cell.

5 July 2018

1 reference

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Development of tau aggregation inhibitors for Alzheimer's disease

5 July 2018

1 reference

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Mechanisms of tau-induced neurodegeneration

5 July 2018

1 reference

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Current concepts in Alzheimer's disease: a multidisciplinary review

5 July 2018

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Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

5 July 2018

1 reference

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Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Is tau aggregation toxic or protective?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structural principles of tau and the paired helical filaments of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

5 July 2018

Amyloid-beta aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Recent progress in understanding hydrophobic interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Single-molecule studies of membrane proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Intrinsically disordered proteins in the neurodegenerative processes: formation of tau protein paired helical filaments and their analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The most infectious prion protein particles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structure and morphology of the Alzheimer's amyloid fibril

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structure of the cross-beta spine of amyloid-like fibrils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tau, tangles, and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tau aggregation is driven by a transition from random coil to beta sheet structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Surface-decoration of microtubules by human tau

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The interaction of proteins with solid surfaces

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The formation of straight and twisted filaments from short tau peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Characterization by atomic force microscopy of Alzheimer paired helical filaments under physiological conditions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Some factors in the interpretation of protein denaturation

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

5 July 2018

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Biomolecular force measurements and the atomic force microscope

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Intermolecular forces in biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Predicting properties of intrinsically unstructured proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The 4 A X-ray structure of a tubulin:stathmin-like domain complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Observing single biomolecules at work with the atomic force microscope.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

A nucleated assembly mechanism of Alzheimer paired helical filaments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structure of the alpha beta tubulin dimer by electron crystallography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

High resolution imaging of native biological sample surfaces using scanning probe microscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Forces contributing to the conformational stability of proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Twisted ribbon structure of paired helical filaments revealed by atomic force microscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Biomolecular imaging with the atomic force microscope

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The hydrophobic effect in protein folding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Direct observation of motion of single F-actin filaments in the presence of myosin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Subunit structure of paired helical filaments in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structural characterization of the core of the paired helical filament of Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Structural aspects of pathology in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Straight and paired helical filaments in Alzheimer disease have a common structural unit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tip-radius-induced artifacts in AFM images of protamine-complexed DNA fibers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Immunocytochemistry of neurofibrillary tangles with antibodies to subregions of tau protein: identification of hidden and cleaved tau epitopes and a new phosphorylation site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Structural analysis of hyperperiodic DNA from Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Accurate length determination of DNA molecules visualized by atomic force microscopy: evidence for a partial B- to A-form transition on mica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

The DeltaK280 mutation in MAP tau favors exon 10 skipping in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

AFM force measurements on microtubule-associated proteins: the projection domain exerts a long-range repulsive force.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Mechanics of forced unfolding of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

The "jaws" of the tau-microtubule interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Locking and Unlocking of Polyelectrolyte Brushes: Toward the Fabrication of Chemically Controlled Nanoactuators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

On the adsorption of proteins on solid surfaces, a common but very complicated phenomenon.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Paired helical filaments are twisted ribbons composed of two parallel and aligned components: image reconstruction and modeling of filament structure using atomic force microscopy.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930729

Tau protein binding forms a 1nm thick layer along protofilaments without affecting the radial elasticity of microtubules

28 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145318

Mesoscopic properties of semiflexible amyloid fibrils

21 January 2018

1 reference

12 December 2020

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

1 reference

12 December 2020

Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation

1 reference

12 December 2020

Presence of two different fibril subtypes in the Pick body: an immunoelectron microscopic study

1 reference

12 December 2020

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure

1 reference

12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

1 reference

12 December 2020

Characterization by atomic force microscopy and cryoelectron microscopy of tau polymers assembled in Alzheimer's disease

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.145318

1 reference

31 July 2017

1 reference

31 July 2017

1 reference