(Q34097195)

31 July 2017

title

Genome architecture of the human beta-globin locus affects developmental regulation of gene expression (English)

1 reference

ORCID Public Data File 2021

31 July 2017

1 reference

author name string

Susanna Harju

1

1 reference

31 July 2017

Patrick A Navas

2

1 reference

31 July 2017

George Stamatoyannopoulos

3

1 reference

31 July 2017

Kenneth R Peterson

4

1 reference

31 July 2017

language of work or name

English

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publication date

1 October 2005

1 reference

Molecular and Cellular Biology

31 July 2017

published in

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31 July 2017

volume

25

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31 July 2017

issue

20

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31 July 2017

page(s)

8765-8778

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Adult stage gamma-globin silencing is mediated by a promoter direct repeat element

31 July 2017

cites work

1 reference

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Multiple interactions between regulatory regions are required to stabilize an active chromatin hub.

5 July 2018

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Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.

5 July 2018

1 reference

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Transgenic mice carrying yeast artificial chromosomes

5 July 2018

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Spatial organization of gene expression: the active chromatin hub.

5 July 2018

1 reference

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Genomic gene clustering analysis of pathways in eukaryotes

5 July 2018

1 reference

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5 July 2018

Locus control regions

1 reference

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Chromatin structure and control of beta-like globin gene switching

5 July 2018

1 reference

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Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

5 July 2018

1 reference

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Locus control regions: coming of age at a decade plus

5 July 2018

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A striking organization of a large family of human neural cadherin-like cell adhesion genes

5 July 2018

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Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

The effect of distance on long-range chromatin interactions

5 July 2018

1 reference

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Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion

5 July 2018

1 reference

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Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

5 July 2018

1 reference

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Binary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expression

5 July 2018

1 reference

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Regulation and activities of alpha-fetoprotein.

5 July 2018

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Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Role of gene order in developmental control of human gamma- and beta-globin gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Developmental regulation of human gamma-globin genes in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Developmental regulation of beta-globin gene switching.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

A fetal globin gene mutation in A gamma nondeletion hereditary persistence of fetal hemoglobin increases promoter strength in a nonerythroid cell

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Developmental regulation of fetal to adult globin gene switching in human fetal erythroid x mouse erythroleukemia cell hybrids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Importance of globin gene order for correct developmental expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Human gamma- to beta-globin gene switching in transgenic mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Homeobox genes and axial patterning

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

The primary structure of the human ε-globin gene

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265765

Sensitive ribonuclease protection assay employing glycogen as a carrier and a single inactivation/precipitation step

28 October 2018

1 reference

12 December 2020

The chemical heterogeneity of the fetal hemoglobin in normal newborn infants and in adults

1 reference

12 December 2020

Human γ-globin genes silenced independently of other genes in the β-globin locus

1 reference

12 December 2020

Production of transgenic mice with yeast artificial chromosomes

1 reference

12 December 2020

10.1128/MCB.25.20.8765-8778.2005

Identifiers

DOI

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31 July 2017

1 reference

31 July 2017

1 reference