(Q34099804)

31 July 2017

Physiologically based absorption modelling to predict the impact of drug properties on pharmacokinetics of bitopertin (English)

1 reference

31 July 2017

1 reference

Neil Parrott

1

1 reference

31 July 2017

Dominik Hainzl

2

1 reference

31 July 2017

Emmanuel Scheubel

3

1 reference

31 July 2017

Siegfried Krimmer

4

1 reference

31 July 2017

Christophe Boetsch

5

1 reference

31 July 2017

Elena Guerini

6

1 reference

31 July 2017

Meret Martin-Facklam

7

1 reference

31 July 2017

language of work or name

English

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publication date

27 June 2014

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31 July 2017

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31 July 2017

16

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31 July 2017

5

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31 July 2017

1077-1084

1 reference

https://scigraph.springernature.com/pub.10.1208/s12248-014-9639-y

31 July 2017

0 references

cites work

The use of modeling tools to drive efficient oral product design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

The role of predictive biopharmaceutical modeling and simulation in drug development and regulatory evaluation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Utility of physiologically based absorption modeling in implementing Quality by Design in drug development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Physiologically-based pharmacokinetics in drug development and regulatory science

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Drug absorption modeling as a tool to define the strategy in clinical formulation development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Pharmaceutical quality by design: product and process development, understanding, and control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Physiologically based pharmacokinetic modelling to predict single- and multiple-dose human pharmacokinetics of bitopertin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

A glimmer of light for neuropsychiatric disorders.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Applications of physiologically based absorption models in drug discovery and development.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Dissolution modeling: factors affecting the dissolution rates of polydisperse powders.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147056

Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24970349

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1208/S12248-014-9639-Y

1 reference

Dimensions Publication ID

31 July 2017

0 references

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31 July 2017

1 reference