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The use of modeling tools to drive efficient oral product design
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scholarly article
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PubMed
title
The use of modeling tools to drive efficient oral product design
(English)
1 reference
stated in
PubMed
author name string
Neil R. Mathias
series ordinal
1
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Crossref
John Crison
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2
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Crossref
language of work or name
English
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PubMed
publication date
September 2012
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PubMed
published in
The AAPS Journal
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Crossref
volume
14
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PubMed
issue
3
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PubMed
page(s)
591-600
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PubMed
cites work
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies
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PubMed Central
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28 September 2017
An update on computational oral absorption simulation
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PubMed Central
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28 September 2017
Utility of physiologically based absorption modeling in implementing Quality by Design in drug development
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28 September 2017
Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science
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PubMed Central
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28 September 2017
Prediction of modified release pharmacokinetics and pharmacodynamics from in vitro, immediate release, and intravenous data
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28 September 2017
Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effects
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PubMed Central
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28 September 2017
Understanding the effect of API properties on bioavailability through absorption modeling
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28 September 2017
From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools
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28 September 2017
Generalization of a prototype intelligent hybrid system for hard gelatin capsule formulation development
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28 September 2017
A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study
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PubMed Central
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28 September 2017
Predicting the impact of physiological and biochemical processes on oral drug bioavailability
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28 September 2017
Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption
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28 September 2017
Comparison between permeability coefficients in rat and human jejunum
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28 September 2017
Biowaiver approach for biopharmaceutics classification system class 3 compound metformin hydrochloride using in silico modeling
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28 November 2018
Predicting orally disintegrating tablets formulations of ibuprophen tablets: an application of the new SeDeM-ODT expert system.
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28 November 2018
Using absorption simulation and gastric pH modulated dog model for formulation development to overcome achlorhydria effect
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28 November 2018
Effect of gastric pH on the pharmacokinetics of a BCS class II compound in dogs: utilization of an artificial stomach and duodenum dissolution model and GastroPlus,™ simulations to predict absorption
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PubMed Central
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28 November 2018
Simulation of human intravenous and oral pharmacokinetics of 21 diverse compounds using physiologically based pharmacokinetic modelling
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PubMed Central
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28 November 2018
The biowaiver extension for BCS class III drugs: the effect of dissolution rate on the bioequivalence of BCS class III immediate-release drugs predicted by computer simulation
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28 November 2018
Mechanism-based prediction of particle size-dependent dissolution and absorption: cilostazol pharmacokinetics in dogs.
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28 November 2018
Computer simulations using GastroPlus to justify a biowaiver for etoricoxib solid oral drug products
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PubMed Central
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28 November 2018
Applications of physiologically based absorption models in drug discovery and development.
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PubMed Central
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28 November 2018
Prediction of human intestinal absorption using an artificial neural network.
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PubMed Central
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28 November 2018
An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery.
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PubMed Central
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28 November 2018
A pH-dilution method for estimation of biorelevant drug solubility along the gastrointestinal tract: application to physiologically based pharmacokinetic modeling
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22644702
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pharmacokinetics of metoprolol in healthy, elderly, non-smoking individuals after a single dose and two weeks of treatment
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22644702
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pharmacokinetic and pharmacodynamic comparison of metoprolol CR/ZOK once daily with conventional tablets once daily and in divided doses
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22644702
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22644702
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Introduction to computational oral absorption simulation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22644702
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1208/S12248-012-9372-3
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Dimensions Publication ID
1035667479
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Fatcat ID
release_uhuwjhcrhve5tewn27myq3rzoi
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/uhuwjhcrhve5tewn27myq3rzoi
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24 November 2022
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PMC publication ID
3385810
1 reference
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PubMed
PubMed publication ID
22644702
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PubMed
ResearchGate publication ID
225073847
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