(Q34101243)

31 July 2017

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title

Cholesterol modification of proteins (English)

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31 July 2017

main subject

Dispatched Dmel_CG2019

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GOA release 2020-03-11

author name string

R K Mann

series ordinal

1

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31 July 2017

P A Beachy

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 December 2000

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Biochimica et Biophysica Acta

31 July 2017

published in

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31 July 2017

volume

1529

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31 July 2017

issue

1-3

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31 July 2017

page(s)

188-202

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Autoproteolysis in hedgehog protein biogenesis

31 July 2017

cites work

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7 January 2021

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

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7 January 2021

Cholesterol modification of hedgehog signaling proteins in animal development

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7 January 2021

Patterning activities of vertebrate hedgehog proteins in the developing eye and brain.

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7 January 2021

Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

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7 January 2021

Induction of midbrain dopaminergic neurons by Sonic hedgehog

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7 January 2021

Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage.

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7 January 2021

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants.

1 reference

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7 January 2021

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

1 reference

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7 January 2021

Identification of a palmitic acid-modified form of human Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

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https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Teratogen-mediated inhibition of target tissue response to Shh signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Breaking up is easy with esters

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Characterization of ERK1 activation site mutants and the effect on recognition by MEK1 and MEK2

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature

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https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Genome sequence of the nematode C. elegans: a platform for investigating biology

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Warthog and groundhog, novel families related to hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Caenorhabditis elegans has scores of hedgehog-related genes: sequence and expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Statistical modeling, phylogenetic analysis and structure prediction of a protein splicing domain common to inteins and hedgehog proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

A helix-turn-helix DNA-binding motif predicted for transposases of DNA transposons

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The long and short of hedgehog signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The world according to hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Transducing Hedgehog: the story so far

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Serpentine proteins slither into the wingless and hedgehog fields

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Dual roles for patched in sequestering and transducing Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Sonic hedgehog signaling by the patched-smoothened receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Biochemical evidence that patched is the Hedgehog receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

RSH/SLO ("Smith-Lemli-Opitz") syndrome: historical, genetic, and developmental considerations

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Genetics of ventral forebrain development and holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: does abnormal cholesterol metabolism affect the function of Sonic Hedgehog?

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Cholesterol, hedgehog and embryogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Defective forebrain development in mice lacking gp330/megalin

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Pathogenesis of malformations in a rodent model for Smith-Lemli-Opitz syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Teratogenic action and embryo lethality of AY 9944R: Prevention by a hypercholesterolemia-provoking diet

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Interaction of cholesterol with various glycerophospholipids and sphingomyelin

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The differential miscibility of lipids as the basis for the formation of functional membrane rafts.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Functional rafts in cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The caveolae membrane system

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Membrane microdomains and caveolae

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Caveolins, liquid-ordered domains, and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

1 reference

7 January 2021

Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2800%2900148-7

7 January 2021

10.1016/S1388-1981(00)00148-7

Identifiers

DOI

1 reference

31 July 2017

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