(Q34102938)

31 July 2017

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title

Neuronal plasticity and stressor toxicity during aging (English)

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31 July 2017

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Brewer GJ

1

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31 July 2017

publication date

1 December 2000

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31 July 2017

published in

Experimental Gerontology

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31 July 2017

volume

35

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31 July 2017

issue

9-10

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31 July 2017

page(s)

1165-1183

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Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons.

31 July 2017

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Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.

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The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease

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Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle

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N-acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice: implications for treatment of Parkinson's disease

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Morphological plasticity of synaptic mitochondria during aging

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7 January 2021

Neuronal subclass-selective loss of pyruvate dehydrogenase immunoreactivity following canine cardiac arrest and resuscitation

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Age-dependent impairment of mitochondrial function in primate brain

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Isolation and culture of adult rat hippocampal neurons

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Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture

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Protective Effect of the Energy Precursor Creatine Against Toxicity of Glutamate and β-Amyloid in Rat Hippocampal Neurons

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Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

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Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation.

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7 January 2021

Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease

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7 January 2021

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease

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7 January 2021

Physical training modifies the age-related decrease of GAP-43 and synaptophysin in the hippocampal formation in C57BL/6J mouse.

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7 January 2021

Calcium currents of embryonic and adult neurons in serum-free culture

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Abnormal properties of creatine kinase in Alzheimer's disease brain: correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning.

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7 January 2021

Nimodipine ameliorates aging-related changes in open-field behaviors of the rabbit

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7 January 2021

Electrophysiology of embryonic, adult and aged rat hippocampal neurons in serum-free culture

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7 January 2021

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

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7 January 2021

Gene expression of ND4, a subunit of complex I of oxidative phosphorylation in mitochondria, is decreased in temporal cortex of brains of Alzheimer's disease patients.

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7 January 2021

Reversible impairment of long-term potentiation in transgenic Cu/Zn-SOD mice.

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7 January 2021

Decrease of rotenone inhibition is a sensitive parameter of complex I damage in brain non-synaptic mitochondria of aged rats.

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7 January 2021

Evidence for mitochondrial K ATP channels as effectors of human myocardial preconditioning

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7 January 2021

The alpha-ketoglutarate dehydrogenase complex in neurodegeneration

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7 January 2021

Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function

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7 January 2021

CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains

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7 January 2021

Functional aspects of creatine kinase in brain.

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7 January 2021

Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Creatine increases survival and suppresses seizures in the hypoxic immature rat.

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7 January 2021

Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type?

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7 January 2021

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7 January 2021

Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

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7 January 2021

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7 January 2021

Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.

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7 January 2021

Brain energy metabolizing enzymes in Alzheimer's disease: alpha-ketoglutarate dehydrogenase complex and cytochrome oxidase

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7 January 2021

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

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7 January 2021

Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity

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7 January 2021

Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients.

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7 January 2021

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

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7 January 2021

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7 January 2021

Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes.

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7 January 2021

Aging and resistance to oxidative damage in Caenorhabditis elegans

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7 January 2021

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

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7 January 2021

Inhibitors of free radical formation fail to attenuate direct beta-amyloid25-35 peptide-mediated neurotoxicity in rat hippocampal cultures.

1 reference

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7 January 2021

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.

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7 January 2021

Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain.

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7 January 2021

Neuroprotective effects of creatine administration against NMDA and malonate toxicity

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

N-Acetylcysteine delays age-associated memory impairment in mice: role in synaptic mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Cytochrome c oxidase in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

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7 January 2021

Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35].

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7 January 2021

Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA

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7 January 2021

Age-dependent alterations in synaptic membrane systems for Ca2+ regulation

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7 January 2021

Decreased plasma membrane calcium transport activity in aging brain

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

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7 January 2021

Low-voltage activated calcium currents increase in basal forebrain neurons from aged rats

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7 January 2021

Increased calcium buffering in basal forebrain neurons during aging

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7 January 2021

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7 January 2021

An in vivo study of phosphorus and glucose metabolism in Alzheimer's disease using magnetic resonance spectroscopy and PET.

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7 January 2021

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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7 January 2021

Cortical cytochrome oxidase activity is reduced in Alzheimer's disease.

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7 January 2021

Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology

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7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

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7 January 2021

Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus

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7 January 2021

Mitochondrial intermembrane inclusion bodies: the common denominator between human mitochondrial myopathies and creatine depletion, due to impairment of cellular energetics

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7 January 2021

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain

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7 January 2021

Genetic and functional changes in mitochondria associated with aging

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7 January 2021

Late onset administration of oral antioxidants prevents age-related loss of motor co-ordination and brain mitochondrial DNA damage.

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7 January 2021

Inhibition of Alzheimer beta-fibrillogenesis by melatonin

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7 January 2021

Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide.

1 reference

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7 January 2021

Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin

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7 January 2021

Cytochrome c oxidase in Alzheimer's disease brain: purification and characterization

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7 January 2021

Electron transport chain defects in Alzheimer's disease brain

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7 January 2021

Alterations of cerebral metabolism in probable Alzheimer's disease: a preliminary study

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7 January 2021

Formation of beta-amyloid protein deposits in brains of transgenic mice

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7 January 2021

Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia.

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7 January 2021

Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats

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7 January 2021

Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease

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7 January 2021

Increased antioxidant enzyme activity in amyloid beta protein-resistant cells

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

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7 January 2021

Human diseases with defects in oxidative phosphorylation. 2. F1F0 ATP-synthase defects in Alzheimer disease revealed by blue native polyacrylamide gel electrophoresis.

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7 January 2021

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

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7 January 2021

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7 January 2021

Expression of superoxide dismutase and catalase in rat brain as a function of age.

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7 January 2021

Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation.

1 reference

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7 January 2021

Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease.

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7 January 2021

Mitochondrial function in brain tissue in primary degenerative dementia.

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7 January 2021

Indomethacin and nordihydroguaiaretic acid inhibition of amyloid beta protein (25-35) activation of phospholipases A2 and D of LA-N-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Rapid Alzheimer-like phosphorylation of tau by the synergistic actions of non-proline-dependent protein kinases and GSK-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Mitochondrial creatine kinase is a prime target of peroxynitrite-induced modification and inactivation.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Mitochondrial creatine kinase: a major constituent of pathological inclusions seen in mitochondrial myopathies

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Risk of Alzheimer's disease and duration of NSAID use.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Glutamate-induced neuron death requires mitochondrial calcium uptake

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Increase in single L-type calcium channels in hippocampal neurons during aging.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Short-term effects of the calcium channel blocker nimodipine (Bay-e-9736) in the management of primary degenerative dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Superoxide dismutase activities in aging rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Age- and concentration-dependent neuroprotection and toxicity by TNF in cortical neurons from beta-amyloid.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Cytosolic Ca2+ binding proteins during rat brain ageing: loss of calbindin and calretinin in the hippocampus, with no change in the cerebellum

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Age-dependent variations in peroxide-utilizing enzymes from rat brain mitochondria and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Cytochrome oxidase in Alzheimer's disease: biochemical, histochemical, and immunohistochemical analyses of the visual and other systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Oxidative damage during aging targets mitochondrial aconitase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

Manganese inhibits mitochondrial aconitase: a mechanism of manganese neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900121-2

7 January 2021

10.1016/S0531-5565(00)00121-2

Identifiers

DOI

1 reference

31 July 2017

1 reference