(Q34103575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

chronic obstructive pulmonary disease

19 January 2020

main subject

0 references

author

Yasuo Kizawa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Ian M. Adcock

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2

Kazuhiro Ito

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Yasuo To

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Marco Failla

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Misako Ito

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Tadashi Kusama

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

W Mark Elliott

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

James C Hogg

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Peter J Barnes

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

11 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Respiratory and Critical Care Medicine

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

182

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

897-904

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

The role of oxidative stress in chronic obstructive pulmonary disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Theophylline in chronic obstructive pulmonary disease: new horizons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthma in general practice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970861

The global burden of disease, 1990–2020

5 July 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Regulation of histone deacetylase 2 by protein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Selective role of PI3K delta in neutrophil inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Phosphoinositide 3-kinase-delta inhibitor reduces vascular permeability in a murine model of asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0937OC

Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20224070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1164/RCCM.200906-0937OC

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224070%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20224070

1 reference