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The RET proto-oncogene in human cancers
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The RET proto-oncogene in human cancers
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
author name string
Jhiang SM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
language of work or name
English
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publication date
1 November 2000
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stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
volume
19
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
page(s)
5590-5597
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
issue
49
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1203857
0 references
cites work
Multiple endocrine neoplasia type 2B mutation in human RET oncogene induces medullary thyroid carcinoma in transgenic mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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GDNF family neurotrophic factor signaling: four masters, one servant?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
The GDNF family ligands and receptors - implications for neural development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
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A RET double mutation in the germline of a kindred with FMTC.
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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The multiple endocrine neoplasia type 2B point mutation switches the specificity of the Ret tyrosine kinase towards cellular substrates that are susceptible to interact with Crk and Nck
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
A potential pathogenetic mechanism for multiple endocrine neoplasia type 2 syndromes involves ret-induced impairment of terminal differentiation of neuroepithelial cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through Ras is essential for ret oncogene-induced cell differentiation in PC12 cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
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Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
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Early cellular abnormalities induced by RET/PTC1 oncogene in thyroid-targeted transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RET rearrangements in papillary thyroid carcinomas and adenomas detected by interphase FISH
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of nerve growth factor-induced terminal differentiation by ret oncogene involves perturbation of nuclear translocation of ERK
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
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inferred from DOI database lookup
Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
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inferred from DOI database lookup
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RET proto-oncogene in the development of human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A two-hit model for development of multiple endocrine neoplasia type 2B by RET mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RET is expressed but not mutated in extra-adrenal paragangliomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential induction of RET/PTC1 rearrangement by X-ray irradiation
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
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inferred from DOI database lookup
Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fusion of a novel gene, ELKS, to RET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic activation of RET by two distinct FMTC mutations affecting the tyrosine kinase domain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through scaffold, anchoring, and adaptor proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different mutations of the RET gene cause different human tumoral diseases.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor signaling by receptor tyrosine kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct frequency of ret rearrangements in papillary thyroid carcinomas of children and adults from Belarus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sporadic ret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by the receptor tyrosine kinase Ret.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of ret oncogenic activation in MEN2 inherited cancer syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203857
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
Dimensions Publication ID
1033777274
0 references
PubMed ID
11114739
1 reference
stated in
Europe PubMed Central
PubMed ID
11114739
retrieved
31 July 2017
ResearchGate publication ID
12212952
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