(Q34106250)

English

Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IκBα.

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Europe PubMed Central

PubMed publication ID

31 July 2017

Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IκBα. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Alzheimer's disease

0 references

phosphorylation

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0 references

Matthias Staufenbiel

4

object named as

Matthias Staufenbiel

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Hong Jiang

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Ping He

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Junxia Xie

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Rena Li

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Yong Shen

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

13 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

4906-4918

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

SUMO and NF-kappaB ties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Distinct differences between TNF receptor 1- and TNF receptor 2-mediated activation of NFkappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

SUMO: a history of modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

SUMO protein modification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

BACE1: the beta-secretase enzyme in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Gene structure and organization of the human beta-secretase (BACE) promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Yin and Yang: complement activation and regulation in Alzheimer’s disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Inflammation in neurodegenerative disease--a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Inflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Cellular mechanisms of beta-amyloid production and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Induced expression of neuronal membrane attack complex and cell death by Alzheimer's beta-amyloid peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

5 July 2018

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Evidence that A beta 42 is the real culprit in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Repeat-induced gene silencing in mammals.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU206

21 January 2018

Expression of macrophage inflammatory protein 1-alpha is elevated in Alzheimer's vessels and is regulated by oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

28 October 2018

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

28 October 2018

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

28 October 2018

A beta peptide deposition in the brains of transgenic mice: evidence for a key event in Alzheimer's disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

28 October 2018

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148612

28 October 2018

Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24824215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24824215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24824215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDU206

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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