(Q34110838)

31 July 2017

title

Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates H(peroxo) and Q proceed by distinct mechanisms (English)

1 reference

31 July 2017

Oxidation Reactions Performed by Soluble Methane Monooxygenase Hydroxylase Intermediates Hperoxo and Q Proceed by Distinct Mechanisms (English)

1 reference

15 June 2024

1 reference

Christine E. Tinberg

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

15 June 2024

Stephen J. Lippard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

15 June 2024

language of work or name

English

0 references

publication date

1 September 2010

1 reference

31 July 2017

14 September 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20681546

full work available at URL

15 June 2024

https://europepmc.org/articles/pmc2935519?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20681546/pdf/?tool=EBI

15 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20681546/?tool=EBI

15 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://europepmc.org/articles/PMC2935519

15 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://europepmc.org/articles/PMC2935519?pdf=render

15 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://doi.org/10.1021/bi1009375

15 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681546

https://pubs.acs.org/doi/pdf/10.1021/bi1009375

15 June 2024

1 reference

15 June 2024

1 reference

31 July 2017

volume

49

1 reference

31 July 2017

issue

36

1 reference

31 July 2017

page(s)

7902-7912

1 reference

Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathway

31 July 2017

cites work

1 reference

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Human deoxyhypusine hydroxylase, an enzyme involved in regulating cell growth, activates O2 with a nonheme diiron center

5 July 2018

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Kinetic isotope effects in hydroxylation reactions effected by cytochrome P450 compounds I implicate multiple electrophilic oxidants for P450-catalyzed oxidations

5 July 2018

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Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study

5 July 2018

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Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions

5 July 2018

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Hydroxylation of C-H bonds at carboxylate-bridged diiron centres

5 July 2018

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Hydroperoxoferric heme intermediate as a second electrophilic oxidant in cytochrome P450-catalyzed reactions.

5 July 2018

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Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations

5 July 2018

1 reference

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Reactions of methane monooxygenase intermediate Q with derivatized methanes

5 July 2018

1 reference

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Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins A list of abbreviations can be found in Section 7.

5 July 2018

1 reference

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Oxygen kinetic isotope effects in soluble methane monooxygenase

5 July 2018

1 reference

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Oxygen activation catalyzed by methane monooxygenase hydroxylase component: proton delivery during the O-O bond cleavage steps.

5 July 2018

1 reference

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Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant

5 July 2018

1 reference

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Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4.

5 July 2018

1 reference

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Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane

5 July 2018

1 reference

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Methane monooxygenase catalyzed oxygenation of 1,1-dimethylcyclopropane. Evidence for radical and carbocationic intermediates

5 July 2018

1 reference

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Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: mechanistic and environmental implications.

5 July 2018

1 reference

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The soluble methane mono-oxygenase of Methylococcus capsulatus (Bath). Its ability to oxygenate n-alkanes, n-alkenes, ethers, and alicyclic, aromatic and heterocyclic compounds

5 July 2018

1 reference

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Structural model studies for the peroxo intermediate P and the reaction pathway from P-->Q of methane monooxygenase using broken-symmetry density functional calculations

5 July 2018

1 reference

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Regulation of methane monooxygenase catalysis based on size exclusion and quantum tunneling

28 October 2018

1 reference

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Stopped-flow Fourier transform infrared spectroscopy of nitromethane oxidation by the diiron(IV) intermediate of methane monooxygenase

28 October 2018

1 reference

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Reactions of the diiron(IV) intermediate Q in soluble methane monooxygenase with fluoromethanes

28 October 2018

1 reference

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Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935519

Substrate hydroxylation in methane monooxygenase: quantitative modeling via mixed quantum mechanics/molecular mechanics techniques

28 October 2018

1 reference

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Nature of the peroxo intermediate of the W48F/D84E ribonucleotide reductase variant: implications for O2 activation by binuclear non-heme iron enzymes

28 October 2018

1 reference

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Dioxygen activation in methane monooxygenase: a theoretical study

28 October 2018

1 reference

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Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations

28 October 2018

1 reference

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Key amino acid residues in the regulation of soluble methane monooxygenase catalysis by component B.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935519

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

28 October 2018

1 reference

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Evaluation of norcarane as a probe for radicals in cytochome p450- and soluble methane monooxygenase-catalyzed hydroxylation reactions

28 October 2018

1 reference

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Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species

28 October 2018

1 reference

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Intermediate Q from soluble methane monooxygenase hydroxylates the mechanistic substrate probe norcarane: evidence for a stepwise reaction

28 October 2018

1 reference

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The Ferroxidase Reaction of Ferritin Reveals a Diferric μ-1,2 Bridging Peroxide Intermediate in Common with Other O2-Activating Non-Heme Diiron Proteins†

28 October 2018

1 reference

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Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

28 October 2018

1 reference

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Kinetics and Activation Thermodynamics of Methane Monooxygenase CompoundQFormation and Reaction with Substrates†

28 October 2018

1 reference

12 December 2020

Electron-transfer reactions of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath)

1 reference

12 December 2020

Transient intermediates of the methane monooxygenase catalytic cycle

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12 December 2020

Peroxodiferric intermediate of stearoyl-acyl carrier protein delta 9 desaturase: oxidase reactivity during single turnover and implications for the mechanism of desaturation

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12 December 2020

Sequencing and analysis of the Mmethylococcus capsulatus (Bath) solublemethane monooxygenase genes

1 reference

12 December 2020

O2 activation by non-heme diiron proteins: identification of a symmetric mu-1,2-peroxide in a mutant of ribonucleotide reductase

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12 December 2020

Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate Q

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12 December 2020

Evidence for two different active oxygen species in cytochrome P450 BM3 mediated sulfoxidation and N-dealkylation reactions

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12 December 2020

O-O bond cleavage and alkane hydroxylation in methane monooxygenase

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12 December 2020

Activation of the hydroxylase of sMMO from Methylococcus capsulatus (Bath) by hydrogen peroxide

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12 December 2020

An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase

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12 December 2020

Substrate specificity of soluble methane monooxygenase. Mechanistic implications

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12 December 2020

Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins

1

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15 June 2024

New Journal of Chemistry

27

15

411

Andersson K. K.

1991

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pH and Secondary Kinetic Isotope Effects on the Reaction ofd-Amino Acid Oxidase with Nitroalkane Anions: Evidence for Direct Attack on the Flavin by Carbanions

15 June 2024

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The Electrogenerated Cyanomethyl Anion in Organic Synthesis

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Mechanistic studies on the hydroxylation of methane by methane monooxygenase.

15 June 2024

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15 June 2024

Identifiers

DOI

10.1021/BI1009375

1 reference

31 July 2017

1 reference

31 July 2017

1 reference