(Q34111582)

31 July 2017

1 reference

title

Using cytochrome P-450 gene knock-out mice to study chemical metabolism, toxicity, and carcinogenicity (English)

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31 July 2017

B I Ghanayem

1

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31 July 2017

H Wang

series ordinal

2

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31 July 2017

S Sumner

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 November 2000

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31 July 2017

published in

Toxicologic Pathology

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31 July 2017

volume

28

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31 July 2017

issue

6

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31 July 2017

page(s)

839-850

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Human cDNA-expressed cytochrome P450 IA2: mutagen activation and substrate specificity

31 July 2017

cites work

1 reference

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Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation

21 January 2018

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Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice.

21 January 2018

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Regulation of cytochrome P4501B1 in cultured rat adrenocortical cells by cyclic adenosine 3',5'-monophosphate and 2,3,7,8- tetrachlorodibenzo-p-dioxin

21 January 2018

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Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

21 January 2018

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Metabolism of Chloroform by Cytochrome P450 2E1 Is Required for Induction of Toxicity in the Liver, Kidney, and Nose of Male Mice

21 January 2018

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A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.

21 January 2018

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Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery

21 January 2018

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Role of CYP1A2 in hepatic sequestration of dioxin: studies using CYP1A2 knock-out mice

21 January 2018

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Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

21 January 2018

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Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

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DNA adducts, cell proliferation and papilloma latency time in mouse skin after repeated dermal application of DMBA and TPA.

21 January 2018

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Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis.

21 January 2018

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

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Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

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Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d

21 January 2018

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The detection of cytochrome P450 2E1 and its catalytic activity in rat testis

21 January 2018

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Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues

21 January 2018

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CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.

21 January 2018

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RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma

21 January 2018

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Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

21 January 2018

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The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects

21 January 2018

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How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress

21 January 2018

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A Novel Adrenocorticotropin-Inducible Cytochrome P450 from Rat Adrenal Microsomes Catalyzes Polycylic Aromatic Hydrocarbon Metabolism*

21 January 2018

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Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice

21 January 2018

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Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice

21 January 2018

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Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2

21 January 2018

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Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

21 January 2018

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Purification and immunological characterization of a novel cytochrome P450 from C3H/10T1/2 cells

21 January 2018

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Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2

21 January 2018

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Regulation of hepatic CYP1A isozymes by piperonyl butoxide and acenaphthylene in the mouse

21 January 2018

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Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity.

21 January 2018

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Catalytic properties of polymorphic human cytochrome P450 1B1 variants.

21 January 2018

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Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

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Localization of cytochrome P1-450 and P3-450 genes to mouse chromosome 9

21 January 2018

1 reference

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10.1177/019262330002800613

21 January 2018

Identifiers

DOI

0 references

1 reference