(Q34111636)

31 July 2017

title

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain (English)

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positron emission tomography

31 July 2017

main subject

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William E Klunk

11

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Bradley Hyman

6

object named as

Bradley T Hyman

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31 July 2017

5

Matthew P Frosch

1 reference

31 July 2017

Chester A Mathis

1

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31 July 2017

Brian J Bacskai

2

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31 July 2017

Stephen T Kajdasz

3

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31 July 2017

Megan E McLellan

4

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31 July 2017

Daniel P Holt

7

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31 July 2017

Yanming Wang

8

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31 July 2017

Guo-Feng Huang

9

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31 July 2017

Manik L Debnath

10

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31 July 2017

language of work or name

English

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publication date

1 February 2002

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Bioorganic & Medicinal Chemistry Letters

31 July 2017

published in

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31 July 2017

volume

12

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31 July 2017

issue

3

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31 July 2017

page(s)

295-298

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Biological markers of Alzheimer's disease

31 July 2017

cites work

1 reference

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7 January 2021

Review of the next generation of Alzheimer's disease therapeutics: challenges for drug development

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Imaging Alzheimer's amyloid

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7 January 2021

Development of small molecule probes for the Beta-amyloid protein of Alzheimer's Disease

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7 January 2021

Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain.

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7 January 2021

99mTc-MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease

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7 January 2021

In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease

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7 January 2021

Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

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7 January 2021

Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.

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7 January 2021

Fundamentals of positron emission tomography and applications in preclinical drug development

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7 January 2021

Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo

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7 January 2021

Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

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7 January 2021

Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.

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7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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7 January 2021

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

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7 January 2021

An improved synthesis of (3-N-[11C]methyl)spiperone

1 reference

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7 January 2021

10.1016/S0960-894X(01)00734-X

Identifiers

DOI

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31 July 2017

1 reference