(Q34112986)

31 July 2017

title

Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance (English)

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31 July 2017

Maria Hinterberger

1

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31 July 2017

Martin Aichinger

2

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31 July 2017

Olivia Prazeres da Costa

3

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31 July 2017

David Voehringer

4

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31 July 2017

Reinhard Hoffmann

5

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31 July 2017

Ludger Klein

6

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31 July 2017

language of work or name

English

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publication date

2 May 2010

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31 July 2017

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31 July 2017

volume

11

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31 July 2017

issue

6

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31 July 2017

page(s)

512-519

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NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

31 July 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1874

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

1 reference

12 December 2020

RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

1 reference

12 December 2020

Quantitative impact of thymic clonal deletion on the T cell repertoire

1 reference

12 December 2020

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

1 reference

12 December 2020

Tissue-specific and reversible RNA interference in transgenic mice

1 reference

12 December 2020

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

1 reference

12 December 2020

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

1 reference

12 December 2020

CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium

1 reference

12 December 2020

Intraclonal competition limits the fate determination of regulatory T cells in the thymus

1 reference

12 December 2020

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

1 reference

12 December 2020

Thymic development and peripheral homeostasis of regulatory T cells.

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12 December 2020

Antigen presentation in the thymus for positive selection and central tolerance induction

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12 December 2020

Dendritic cells in the thymus contribute to T-regulatory cell induction

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12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

1 reference

12 December 2020

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

1 reference

12 December 2020

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

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12 December 2020

Deletional tolerance mediated by extrathymic Aire-expressing cells

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12 December 2020

Heterogeneity of thymic dendritic cells

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12 December 2020

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

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12 December 2020

Regulation of MHC class II gene expression by the class II transactivator

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12 December 2020

Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.

1 reference

12 December 2020

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

1 reference

12 December 2020

The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

1 reference

12 December 2020

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

1 reference

12 December 2020

Central tolerance: learning self-control in the thymus

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12 December 2020

Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance

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12 December 2020

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

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12 December 2020

Bioconductor: open software development for computational biology and bioinformatics

1 reference

12 December 2020

Revisiting the specificity of the MHC class II transactivator CIITA in vivo.

1 reference

12 December 2020

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

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12 December 2020

Cloning of short hairpin RNAs for gene knockdown in mammalian cells.

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12 December 2020

TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes

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12 December 2020

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

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12 December 2020

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

12 December 2020

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

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12 December 2020

Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

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12 December 2020

Kinetics of generation and persistence on membrane class II molecules of a viral peptide expressed on foreign and self proteins

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12 December 2020

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

1 reference

12 December 2020

Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

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12 December 2020

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

1 reference

12 December 2020

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12 December 2020

A two-step process for thymic regulatory T cell development.

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12 December 2020

Projection of an immunological self shadow within the thymus by the aire protein

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12 December 2020

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

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12 December 2020

Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

1 reference

12 December 2020

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

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12 December 2020

Sampling of complementing self-antigen pools by thymic stromal cells maximizes the scope of central T cell tolerance

1 reference

12 December 2020

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

1 reference

12 December 2020

The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription

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12 December 2020

Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development

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12 December 2020

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus

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12 December 2020

Intercellular MHC transfer between thymic epithelial and dendritic cells

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12 December 2020

Identifiers

DOI

10.1038/NI.1874

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Dimensions Publication ID

31 July 2017

1033981395

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