(Q34117201)

English

Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

31 July 2017

Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

0 references

1 reference

based on heuristic

inferred from title

author name string

Vellareddy Anantharam

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Masashi Kitazawa

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Jarrad Wagner

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Siddharth Kaul

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Anumantha G Kanthasamy

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 March 2002

1 reference

Europe PubMed Central

31 July 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

22

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

1738-1751

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Intracellular delivery of proteins with a new lipid-mediated delivery system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C isozymes and the regulation of diverse cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The physiopathologic significance of manganese in brain: its relation to schizophrenia and neurodegenerative disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of protein kinase C-delta in DNA damage-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKC-δ is an apoptotic lamin kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occupational metal exposures and the risk of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese: brain transport and emerging research needs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of intracellular Cd2+ in catecholamine release and lethality in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial role in life and death of the cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of grafted immortalized dopamine neurons in an animal model of parkinsonism: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: the executioners of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylcyclopentadienyl manganese tricarbonyl: health risk uncertainties and research directions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial permeability transition pore and its role in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiological survey among workers exposed to manganese: effects on lung, central nervous system, and some biological indices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese induced parkinsonism: an outbreak due to an unrepaired ventilation control system in a ferromanganese smelter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell type-specific responses to menadione-induced oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rottlerin, a novel protein kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of methylcyclopentadienyl manganese tricarbonyl (MMT) of rat liver mitochondria. I. Effects, in vitro, on the oxidative phosphorylation (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson disease in twins: an etiologic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappa B activation in tumor necrosis factor alpha-stimulated neutrophils is mediated by protein kinase Cdelta. Correlation to nuclear Ikappa Balpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Airborne manganese particulates and methylcyclopentadienyl manganese tricarbonyl (MMT) at selected outdoor sites in Montreal.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic effects of methylcyclopentadienyl manganese tricarbonyl (MMT) in the mouse: basis of MMT-induced seizure activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat-shock protein-25/27 phosphorylation by the delta isoform of protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H2B phosphorylation in mammalian apoptotic cells. An association with DNA fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A possible role for PKC delta in cerebellar granule cells apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible environmental, occupational, and other etiologic factors for Parkinson's disease: a case-control study in Germany.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative toxicokinetics of manganese chloride and methylcyclopentadienyl manganese tricarbonyl (MMT) in Sprague-Dawley rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic manganese poisoning. Clinical picture and manganese turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria and ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of neurotoxicity and identification of cellular subsets in a three-dimensional brain model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese in the U.S. gasoline supply.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental risk factors and Parkinson's disease: a case-control study in Taiwan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evolution of a mechanism of cell suicide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous neutrophil apoptosis involves caspase 3-mediated activation of protein kinase C-delta

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C delta is essential for etoposide-induced apoptosis in salivary gland acinar cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death mechanisms in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The accuracy of mothers' reports of child vaccination: evidence from rural Egypt

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria and programmed cell death: back to the future.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis and animal studies of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of PKC-isoform-specific biological actions using pharmacological approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in brain dopamine and GABA following inorganic or organic manganese administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11880503

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-05-01738.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758879&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34117201&oldid=1719449836"