(Q34117810)

31 July 2017

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title

Serotonin releasing agents. Neurochemical, therapeutic and adverse effects (English)

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31 July 2017

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Richard B Rothman

1

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31 July 2017

Michael H Baumann

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 April 2002

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Pharmacology, Biochemistry and Behavior

31 July 2017

published in

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31 July 2017

volume

71

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31 July 2017

issue

4

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31 July 2017

page(s)

825-836

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Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group

31 July 2017

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Cardiovascular safety of second-generation antihistamines

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Intravenous administration of the serotonin agonist m-chlorophenylpiperazine (mCPP) increases extracellular serotonin in the diencephalon of awake rats

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The serotonin agonist m-chlorophenylpiperazine (mCPP) binds to serotonin transporter sites in human brain

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Functional consequences of central serotonin depletion produced by repeated fenfluramine administration in rats.

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1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain

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The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

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Dissociation of serotonergic regulation of anxiety and ethanol self-administration: a study with mCPP

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Pharmacokinetics of fenfluramine and norfenfluramine in volunteers given D- and DL-fenfluramine for 15 days

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7 January 2021

Effects of chronic treatment with dexfenfluramine on serotonin in rat blood, brain and lung tissue

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Cloning and expression of the mouse serotonin transporter

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Quantitation of dexfenfluramine/d-norfenfluramine concentration in primate brain using 19F NMR spectroscopy.

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Measurement of human brain dexfenfluramine concentration by 19F magnetic resonance spectroscopy

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Obesity drugs and the heart

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Valvular heart disease associated with fenfluramine-phentermine

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Carrier-dependent and Ca(2+)-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylendioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine.

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7 January 2021

Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability

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7 January 2021

Dexfenfluramine. An updated review of its therapeutic use in the management of obesity

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7 January 2021

Fenfluramine and dextroamphetamine treatment of childhood hyperactivity. Clinical and biochemical findings.

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7 January 2021

Multiple serotonin receptors: opportunities for new treatments for obesity?

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7 January 2021

Effects of mCPP on the extracellular concentrations of serotonin and dopamine in rat brain.

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7 January 2021

Aminorex to Fen/Phen: an epidemic foretold

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7 January 2021

Aminorex to fen/phen: an epidemic foretold

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7 January 2021

Blood pressure and plasma norepinephrine responses to dexfenfluramine in obese postmenopausal women

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7 January 2021

Biological actions of drugs affecting serotonin and eating

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7 January 2021

Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system

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7 January 2021

Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine

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7 January 2021

Differential effects of monoaminergic agonists on alcohol intake in rats fed a tryptophan-enhanced diet

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7 January 2021

Effects of phentermine and fenfluramine on alcohol consumption and alcohol withdrawal seizures in rats

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7 January 2021

A comparison of sibutramine and dexfenfluramine in the treatment of obesity

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7 January 2021

Increased plasma serotonin in primary pulmonary hypertension

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7 January 2021

Influence of 5-HT3 receptor antagonists and the indirect 5-HT agonist, dexfenfluramine, on heroin self-administration in rats.

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7 January 2021

Novel in vivo electrophysiological assay for the effects of cocaine and putative "cocaine antagonists" on dopamine transporter activity of substantia nigra and ventral tegmental area dopamine neurons.

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7 January 2021

The effects of drugs used to treat obesity on the autonomic nervous system

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7 January 2021

Combined serotonin and dopamine indirect agonists correct alcohol craving and alcohol-associated neuroses.

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7 January 2021

Efflux studies allow further characterisation of the noradrenaline and 5-hydroxytryptamine transporters in rat lungs

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7 January 2021

A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation

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7 January 2021

Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA).

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7 January 2021

D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain

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7 January 2021

Effect of dexfenfluramine treatment on body weight, blood pressure and noradrenergic activity in obese hypertensive patients

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7 January 2021

Ethanol consumption following acute fenfluramine, fluoxetine, and dietary tryptophan

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7 January 2021

BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension

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7 January 2021

Pulmonary hypertension, anorexigens and 5-HT: pharmacological synergism in action?

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7 January 2021

Allometric issues in drug development

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7 January 2021

Simultaneous effects of p-chloroamphetamine, d-fenfluramine, and reserpine on free and stored 5-hydroxytryptamine in brain and blood

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7 January 2021

Somatodendritic alpha2-adrenoceptors in the locus coeruleus are involved in the in vivo modulation of cortical noradrenaline release by the antidepressant desipramine

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7 January 2021

Dexfenfluramine. A review of its pharmacological properties and therapeutic potential in obesity

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7 January 2021

In vitro and in vivo effects of the anorectic agent dexfenfluramine on the central serotoninergic neuronal systems of non-human primates. A comparison with the rat

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7 January 2021

Novel synergistic treatment of ethanol withdrawal seizures in rats with dopamine and serotonin agonists

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7 January 2021

Neurotoxicity of MDMA and related compounds: anatomic studies

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7 January 2021

Effects of dopamine and serotonin-releasing agents on methamphetamine discrimination and self-administration in rats.

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7 January 2021

Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA).

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7 January 2021

Correlation between steady-state plasma concentrations of mianserin and trazodone in depressed patients

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7 January 2021

The addition of dexfenfluramine to fluoxetine in the treatment of obesity: a randomized clinical trial

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7 January 2021

Serotonin-releasing effects of substituted piperazines in vitro

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7 January 2021

Fenfluramine: a review of its pharmacological properties and therapeutic efficacy in obesity

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7 January 2021

Effects of chronic fenfluramine on blood serotonin, cerebrospinal fluid metabolites, and behavior in monkeys

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7 January 2021

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

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7 January 2021

Valvular heart disease associated with fenfluramine-phentermine

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7 January 2021

Pharmacologic induction of weight loss to treat type 2 diabetes.

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7 January 2021

Anorexigens and pulmonary hypertension in the United States: results from the surveillance of North American pulmonary hypertension

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7 January 2021

Suppression of eating by fenfluramine in patients with bulimia nervosa.

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7 January 2021

Treatment of alcohol and cocaine addiction by the combination of pemoline and fenfluramine: a preliminary case series.

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7 January 2021

Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension

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7 January 2021

Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

1 reference

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7 January 2021

Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: a pharmacological strategy for treating stimulant abuse

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7 January 2021

Chronic treatment with phentermine combined with fenfluramine lowers plasma serotonin.

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7 January 2021

Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

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7 January 2021

Primary pulmonary hypertension

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7 January 2021

From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters

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7 January 2021

Systemic uptake inhibition decreases serotonin release via somatodendritic autoreceptor activation

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7 January 2021

Antiobesity pharmacotherapy in the management of type 2 diabetes

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7 January 2021

Guanfacine in essential hypertension: effect on blood pressure, plasma noradrenaline concentration and plasma renin activity

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7 January 2021

The effects of fenfluramine (hydrochloride) on the behaviors of fifteen autistic children.

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7 January 2021

Electrophysiological effects of fluoxetine and duloxetine in the dorsal raphe nucleus and hippocampus.

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7 January 2021

Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation.

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7 January 2021

Serotonin: it's possible to have too much of a good thing

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7 January 2021

Effects of fenfluramine on eight outpatients with the syndrome of autism.

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7 January 2021

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

1 reference

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7 January 2021

Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

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7 January 2021

Further studies to examine the nature of dexfenfluramine-induced suppression of heroin self-administration.

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7 January 2021

A comparison of the acute effects of dextroamphetamine and fenfluramine in depression

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https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900669-4

7 January 2021

Drug treatment of obesity

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7 January 2021

A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination

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7 January 2021

Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction

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7 January 2021

An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-Release Dexfenfluramine Study Group

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7 January 2021

The Effects of Dexfenfluramine on Blood Glucose Control in Patients with Type 2 Diabetes

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https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900669-4

7 January 2021

Obese patients with type 2 diabetes poorly controlled by insulin and metformin: effects of adjunctive dexfenfluramine therapy on glycaemic control

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7 January 2021

An investigation into the effects of 5-HT agonists and receptor antagonists on ethanol self-administration in the rat

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7 January 2021

Oxidation of serotonin by superoxide radical: implications to neurodegenerative brain disorders

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7 January 2021

Amphetamine and fenfluramine suppress ethanol intake in ethanol-dependent rats

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https://api.crossref.org/works/10.1016%2FS0091-3057%2801%2900669-4

7 January 2021

Anxiety disorders: a review of tricyclic antidepressants and selective serotonin reuptake inhibitors.

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7 January 2021

10.1016/S0091-3057(01)00669-4

Identifiers

DOI

1 reference

31 July 2017

1 reference