(Q40468890)

20 September 2017

1 reference

title

Fenfluramine: a review of its pharmacological properties and therapeutic efficacy in obesity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A765100

26 July 2022

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2

R N Brogden

1 reference

20 September 2017

R. M. Pinder

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A765100

26 July 2022

P. R. Sawyer

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A765100

26 July 2022

T. M. Speight

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A765100

26 July 2022

G. S. Avery

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A765100

26 July 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=765100

26 July 2022

publication date

1 January 1975

1 reference

20 September 2017

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20 September 2017

10

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20 September 2017

4

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20 September 2017

241-323

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https://scigraph.springernature.com/pub.10.2165/00003495-197510040-00001

20 September 2017

0 references

cites work

Fenfluramine in the treatment of obesity

1 reference

12 December 2020

Letter: Fenfluramine and psychosis

1 reference

12 December 2020

The mechanism of action of fenfluramine

1 reference

12 December 2020

Fenfluramine and critical flicker frequency

1 reference

12 December 2020

The metabolic effects, and the composition of the tissue lost, in weight reduction by obese patients on treatment with fenfluramine

1 reference

12 December 2020

The effect of a low-calorie diet with and without fenfluramine on the glucose tolerance and insulin secretion of obese maturity-onset diabetics

1 reference

12 December 2020

Hypotensive effect of fenfluramine in the treatment of obesity

1 reference

12 December 2020

The effect of fenfluramine on glucose tolerance, insulin, lipid and lipoprotein levels in patients with peripheral arterial disease

1 reference

12 December 2020

DNA synthesis in adipose tissue

1 reference

12 December 2020

The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity

1 reference

12 December 2020

Fenfluramine withdrawal and epilepsy

1 reference

12 December 2020

A PRELIMINARY TRIAL OF FENFLURAMINE IN GENERAL PRACTICE

1 reference

12 December 2020

The effect of fenfluramine and its derivatives on triglyceride secretion by the liver of the rabbit

1 reference

12 December 2020

Structure-activity relationships in psychotomimetic phenylalkylamines

1 reference

12 December 2020

A treatment for refractory obesity using fenfluramine without dietary restriction

1 reference

12 December 2020

A comparative trial of fenfluramine and diethylpropion inbesity

1 reference

12 December 2020

1 reference

12 December 2020

[Effects of fenfluramine, administered on short or long-term basis, on lipolysis of obese subjects]

1 reference

12 December 2020

Anti-amphetamine activity of fenfluramine and S 992 in the isolated tail artery of the rat

1 reference

12 December 2020

Action of fenfluramine on monoamine stores of rat tissues

1 reference

12 December 2020

The absorption and urinary excretion in man of fenfluramine and its main metabolite

1 reference

12 December 2020

1 reference

12 December 2020

Effect of fenfluramine and dexamphetamine on pyruvate kinase

1 reference

12 December 2020

A new group of anorexigenic compounds

1 reference

12 December 2020

Effect of fennfluramine on alcohol and saccharin consumption in the rat

1 reference

12 December 2020

The use of anorexigenic drugs in the treatment of diabetes mellitus

1 reference

12 December 2020

Proceedings: The effect of norfenfluramine on thermoregulation in the rabbit

1 reference

12 December 2020

Comparison of the time course of the anorectic effect of fenfluramine and amphetamine with drug levels in blood

1 reference

12 December 2020

Comparative action of fenfluramine and amphetamine in rats with hypothalamic obesity

1 reference

12 December 2020

Norfenfluramine and serotonin turnover rate in the rat brain

1 reference

12 December 2020

The anorectic activity of fenfluramine

1 reference

12 December 2020

The inhibitory effect of fenfluramine on pancreatic lipase activity

1 reference

12 December 2020

Side effects associated with prolonged use of fenfluramine

1 reference

12 December 2020

Effects of two slimming drugs on sleep.

1 reference

12 December 2020

The non-medical misuse of fenfluramine by drug-dependent young South Africans

1 reference

12 December 2020

Effects of various anorexigenic agents on open field behavior of rats

1 reference

12 December 2020

Fenfluramine and 780SE in experimental alcoholism in rats

1 reference

12 December 2020

A six month study of a carbohydrate restricted diet in the management of maturity-onset diabetes and an evaluation of fenfluramine in patients unresponsive to this diet

1 reference

12 December 2020

EEG profiles of fenfluramine, amobarbital and dextroamphetamine in normal volunteers

1 reference

12 December 2020

CARDIOVASCULAR AND AUTONOMIC EFFECTS OF FENFLURAMINE HYDROCHLORIDE

1 reference

12 December 2020

Correlation between Bile Secretion and Triglyceride Release in Perfused Rat Liver and Some Effects of Fenfluramine

1 reference

12 December 2020

The possible central stimulant mechanisms of some appetite suppressants

1 reference

12 December 2020

Drug-dependent south African national servicemen.

1 reference

12 December 2020

Proceedings: Effect of fenfluramine and norfenfluramine on glucose uptake by the isolated rat diaphragm.

1 reference

12 December 2020

Subjective effects of two anorexigenic agents--fenfluramine and AN 448 in normal subjects

1 reference

12 December 2020

Sleep-waking patterns in cats after administration of fenfluramine and other monoaminergic modulating drugs.

1 reference

12 December 2020

Dissociation of the anorexic effects of fenfluramine and amphetamine following intrahypothalamic injection

1 reference

12 December 2020

Effect of fenfluramine on blood-lipids in man.

1 reference

12 December 2020

Effect of diet, sulphonylureas, and phenformin on peripheral glucose uptake in diabetes and obesity

1 reference

12 December 2020

The Management of Obesity

1 reference

12 December 2020

Fenfluramine and methylcellulose in the treatment of obesity: the relationship between plasma drug concentrations and therapeutic efficacy

1 reference

12 December 2020

Characteristics of the human lymphocyte insulin receptor

1 reference

12 December 2020

Behavioural and biochemical effects of fenfluramine in patients with neurologic disease

1 reference

12 December 2020

Assessment of new formulation of fenfluramine in the management of the obese, diabetic African

1 reference

12 December 2020

Effects of fenfluramine on sleep-wakefulness in cats

1 reference

12 December 2020

Fenfluramine overdosage in childhood. Case report

1 reference

12 December 2020

Experimental evidence for imipramine like activity of fenfluramine.

1 reference

12 December 2020

Prolonged total fasting for obesity.

1 reference

12 December 2020

A comparison of the effects of fenfluramine and amphetamine on uptake release and catabolism of norepinephrine in rat brain.

1 reference

12 December 2020

Role of catecholamines in the anorectic effects of amphetamine in rats

1 reference

12 December 2020

Withdrawal Depression in Obese Patients after Fenfluramine Treatment

1 reference

12 December 2020

[The influence of appetite depressants on carbohydrate and fatty acid metabolism]

1 reference

12 December 2020

Prolonged action fenfluramine in general practice

1 reference

12 December 2020

Human autonomic pharmacology. XVI. Benzedrine sulfate as an aid in the treatment of obesity. 1938.

1 reference

12 December 2020

Effect of fenfluramine on appetite and lipid metabolism of the young ruminant.

1 reference

12 December 2020

Addiction or dependence?

1 reference

12 December 2020

Some effects of fenfluramine and its derivatives on the central catecholaminergic systems of mice

1 reference

12 December 2020

1 reference

12 December 2020

5,6-Dihydroxytryptamine: suppression of the anorexigenic action of fenfluramine.

1 reference

12 December 2020

A controlled investigation of the "glycolyptic" action of fenfluramine

1 reference

12 December 2020

The effects of chronic fenfluramine administration on behaviour and body weight

1 reference

12 December 2020

Treatment of obesity with fenfluramine.

1 reference

12 December 2020

The effects of fenfluramine on fixed ratio responding

1 reference

12 December 2020

The effect of dietary restriction and anorectic drugs on linear growth velocity in childhood obesity

1 reference

12 December 2020

Action of fenfluramine

1 reference

12 December 2020

Fenfluramine in obese patients on various antihypertensive drugs. Double-blind controlled trial

1 reference

12 December 2020

Appetite suppressants and pulmonary hypertension.

1 reference

12 December 2020

Stimulation by Fenfluramine of Glucose Uptake into Skeletal Muscle In Vitro

1 reference

12 December 2020

Toxicologic studies of fenfluramine

1 reference

12 December 2020

Depression following fenfluramine withdrawal

1 reference

12 December 2020

A comparison of the efficacy and acceptability of fenfluramine tablets (BP) and prolonged action capsules

1 reference

12 December 2020

Influence of a long acting preparation of fenfluramine on body weight, body composition and skinfold thickness in obese subjects

1 reference

12 December 2020

Hypoglycemic Action of Fenfluramine in Diabetes Mellitus

1 reference

12 December 2020

The effects of acutely administered fenfluramine on activity and eating behaviour

1 reference

12 December 2020

A trial of fenfluramine in children with obesity associated with reduced muscle activity

1 reference

12 December 2020

Biphasic action of a 5-hydroxytryptamine inhibitor on fenfluramine-induced anorexia.

1 reference

12 December 2020

Letter: Fenfluramine in complicated obesity

1 reference

12 December 2020

A comparative study of the pharmacologic actions of amphetamine and fenfluramine.

1 reference

12 December 2020

Fenfluramine blockade of CNS stimulant effects of amphetamines

1 reference

12 December 2020

Follow-up Study of Physical Growth of Children Who Had Excessive Weight Gain in First Six Months of Life

1 reference

12 December 2020

Drugs of Dependence Though Not of Abuse: Fenfluramine and Imipramine

1 reference

12 December 2020

Fenfluramine (Ponderax) in the Treatment of Obese Psychiatric Out-patients

1 reference

12 December 2020

Fenfluramine: evidence for a neurotoxic action on midbrain and a long-term depletion of serotonin

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

A trial of fenfluramine (PACaps) and diet in overweight diabetic patients

1 reference

12 December 2020

A collaborative investigation of fenfluramine. Anorexigenic with sedative properties

1 reference

12 December 2020

Fenfluramine in the treatment of obesity

1 reference

12 December 2020

Thermogenic properties of norfenfluramine

1 reference

12 December 2020

Psychomotor Test Performance with a Fenfluramine-Amphetamine Combination

1 reference

12 December 2020

Effects of fenfluramine and related compounds on the synthesis of glycerolipids by rat liver

1 reference

12 December 2020

Studies on the site of action of a new anorectic agent, fenfluramine.

1 reference

12 December 2020

Comparative effects of four antiobesity agents on blood plasma lipids in man

1 reference

12 December 2020

The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of 1-14C-glucose by human adipose tissue

1 reference

12 December 2020

A double-blind clinical trial of fenfluramine in the treatment of obesity

1 reference

12 December 2020

Intermittent treatment with anorectic drugs

1 reference

12 December 2020

Fenfluramine in man: hypophagia associated with diminished serotonin turnover

1 reference

12 December 2020

Effect of fenfluramine on the intestinal absorption of triglycerides.

1 reference

12 December 2020

Fenfluramine: amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey.

1 reference

12 December 2020

A clinical trial of fenfluramine in obese children

1 reference

12 December 2020

The central hypotensive action of amphetamine, ephedrine, phentermine, chlorphentermine and fenfluramine

1 reference

12 December 2020

Fenfluramine in the treatment of psoriasis. A preliminary report

1 reference

12 December 2020

Some 5-hydroxytryptamine-like actions of fenfluramine: a comparison with (+)-amphetamine and diethylpropion.

1 reference

12 December 2020

Treatment of refractory obesity with fenfluramine

1 reference

12 December 2020

Amphetamine analogues and brain amines

1 reference

12 December 2020

Hyperpyrexia and overdose

1 reference

12 December 2020

Subjective effects of two anorexigenic agents fenfluramine and AN 448 in amphetamine-dependent subjects

1 reference

12 December 2020

Insulin secretion and hydrocarbon tolerance in essential obesity in women (influence of fenfluramine, phenformin and D-amphetamine)

1 reference

12 December 2020

A double-blind evaluation of fenfluramine in anxious somatizing neurotic medical clinic patients.

1 reference

12 December 2020

Toxic and therapeutic effects of EMTP in obesity

1 reference

12 December 2020

Circulatory effects of fenfluramine in obese hypertensive patients.

1 reference

12 December 2020

Comparative effects of ten anorectic drugs on sleep-wakefulness patterns in cats

1 reference

12 December 2020

Effect of fenfluramine on the electrical activity of the hypothalamic feeding centers

1 reference

12 December 2020

Letter: Abuse of fenfluramine

1 reference

12 December 2020

A double-blind clinical trial of an appetite depressant, fenfluramine, in general practice

1 reference

12 December 2020

Chronic fenfluramine administration: some cerebral effects

1 reference

12 December 2020

A clinical trial of fenfluramine

1 reference

12 December 2020

Species-dependent effects of fenfluramine on the central nervous system

1 reference

12 December 2020

Fenfluramine in mania.

1 reference

12 December 2020

Fenfluramine. Anorexigenic drug in obstetrical practice

1 reference

12 December 2020

Sebum excretion rate and biochemistry in patients with acne vulgaris treated by oral fenfluramine

1 reference

12 December 2020

Fenfluramine in obesity

1 reference

12 December 2020

[The excretion of anorectic phenylalkylamines in the urine]

1 reference

12 December 2020

Study on the excretion, localization and metabolism of a new anorexigenic substance: fenfluramine

1 reference

12 December 2020

Fenfluramine in corticosteroid-induced obesity

1 reference

12 December 2020

The Effect of Drugs on Lipogenesis from Glucose and Palmitate in Human Adipose Tissue

1 reference

12 December 2020

The effects of selective lesioning of brain serotonin or catecholamine containing neurones on the anorectic activity of fenfluramine and amphetamine

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Fenfluramine Metabolism

1 reference

12 December 2020

A double-blind clinical trial of fenfluramine.

1 reference

12 December 2020

1 reference

12 December 2020

The effect of fenfluramine on obesity and plasma lipids of patients with renal allografts

1 reference

12 December 2020

Metabolic effects of fenfluramine--a double-blind study

1 reference

12 December 2020

[Hypoglycemic action of fenfluramine in obese diabetics]

1 reference

12 December 2020

Influence of fenfluramine on the weekly curve of weight loss during obesity

1 reference

12 December 2020

Fenfluramine and triglyceride synthesis by microsomes of the intestinal mucosa in the rat

1 reference

12 December 2020

Comparison of fenfluramine (with ad libitum food intake) with 1,000 calorie diet in obesity

1 reference

12 December 2020

Fenfluramine: study of its central action through its effects on sleep

1 reference

12 December 2020

Assessment of reinforcing properties of amphetamine analogues in self-administering rats

1 reference

12 December 2020

The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine

1 reference

12 December 2020

Absorption, distribution and metabolism of fenfluramine

1 reference

12 December 2020

Fenfluramine overdosage.

1 reference

12 December 2020

The role of norfenfluramine in fenfluramine-induced mydriasis

1 reference

12 December 2020

Effect of fenfluramine on human growth hormone release

1 reference

12 December 2020

Comparison of continuous and intermittent anorectic therapy in obesity.

1 reference

12 December 2020

Methamphetamine, fenfluramine and their N-dealkylated metabolites: effect on monoamine concentrations in rat tissues

1 reference

12 December 2020

Letter: Dyskinesia after fenfluramine

1 reference

12 December 2020

Role of monoamines in the anorexigenic actions of fenfluramine, amphetamine and p-chloromethamphetamine

1 reference

12 December 2020

The effect of a low-calorie diet with and without fenfluramine, and fenfluramine alone on the glucose tolerance and insulin secretion of overweight non-diabetics

1 reference

12 December 2020

Fenfluramine and norfenfluramine on glucose uptake into skeletal muscle

1 reference

12 December 2020

Dangers of certain appetite suppressants.

1 reference

12 December 2020

Central nervous system effects of fenfluramine hydrochloride

1 reference

12 December 2020

Gas chromatographic measurement of levels of fenfluramine and norfenfluramine in human plasma red cells and urine following therapeutic doses

1 reference

12 December 2020

Bioavailability of prolonged action fenfluramine

1 reference

12 December 2020

1 reference

12 December 2020

Pharmacokinetics of absorption, distribution and elimination of fenfluramine and its main metabolite in man.

1 reference

12 December 2020

Fenfluramine, a new anorexigenic agent

1 reference

12 December 2020

Central action of anorexic agents: effects of amphetamine and fenfluramine in rats with lateral hypothalamic lesions.

1 reference

12 December 2020

A comparative trial of different regimens of fenfluramine and phentermine in obesity

1 reference

12 December 2020

Effect of fenfluramine on steady state plasma levels of amitriptyline

1 reference

12 December 2020

The effects of fenfluramine and 780SE on fat absorption

1 reference

12 December 2020

Some cardiovascular and autonomic effects of fenfluramine hydrochloride.

1 reference

12 December 2020

Effects and indications of fenfluramine in the treatment of obesity

1 reference

12 December 2020

Comparison of fenfluramine and metformin in treatment of obesity.

1 reference

12 December 2020

Psychometric studies on sleep for the evaluation of central effects of drugs. The effects of fenfluramine on sleep

1 reference

12 December 2020

Comparison of a new anorectic agent AN 448 with fenfluramine in the treatment of refractory obesity

1 reference

12 December 2020

Prolonged-action fenfluramine in non-diabetic patients with refractory obesity

1 reference

12 December 2020

Effects of fenfluramine-amphetamine combination on psychomotor activity

1 reference

12 December 2020

Effect of long-term fenfluramine treatment on drug-metabolism in rat

1 reference

12 December 2020

On the effect of anorectic drugs on striatum homovanillic acid in rats.

1 reference

12 December 2020

Editorial: Drugs causing weight gain

1 reference

12 December 2020

Prolonged action fenfluramine capsules versus fenfluramine tablets in general practice

1 reference

12 December 2020

Fenfluramine in the management of obesity

1 reference

12 December 2020

Plasma concentrations of fenfluramine and its metabolite, norfenfluramine, after single and repeated oral administration

1 reference

12 December 2020

Letter: Fenfluramine and dreaming

1 reference

12 December 2020

N-ethyl-alpha-methyl-alpha-(m-trifluoromethylbenzyl)nitrone--the major in vitro metabolic product of fenfluramine in guinea-pig liver microsomal fractions.

1 reference

12 December 2020

Antagonism by methysergide of the 5-hydroxytryptamine-like action of toxic doses of fenfluramine in dogs

1 reference

12 December 2020

On the in vivo and in vitro actions of fenfluramine and its derivatives on central monoamine neurons, especially 5-hydroxytryptamine neurons, and their relation to the anorectic activity of fenfluramine

1 reference

12 December 2020

A clinical trial of a new fenfluramine preparation (Ponderax PA)

1 reference

12 December 2020

Proceedings: Effect of the (minus)- and (plus)-isomers of fenfluramine and norfenfluramine on glucose uptake by the isolated rat hemidiaphragm

1 reference

12 December 2020

Appetite suppression and central nervous system stimulation in the rhesus monkey

1 reference

12 December 2020

Fenfluramine and pigmented naevi

1 reference

12 December 2020

1 reference

12 December 2020

A comparative trial of fenfluramine and diethylpropion in obese, hypertensive patients

1 reference

12 December 2020

Effect of fenfluramine on the single neuron activities of the hypothalamic feeding centers

1 reference

12 December 2020

Hormonal and metabolic studies of the action of fenfluramine in normal man, obesity, acromegaly and diabetes mellitus

1 reference

12 December 2020

1 reference

12 December 2020

Unusual effect of fenfluramine

1 reference

12 December 2020

Infantile Overnutrition among Artificially Fed Infants in the Sheffield Region

1 reference

12 December 2020

Unusual effect of fenfluramine

1 reference

12 December 2020

Fenfluramine dependence

1 reference

12 December 2020

Anorexigenic effects of fenfluramine hydrochloride in rats, guinea pigs, and dogs

1 reference

12 December 2020

Diazepam for fenfluramine intoxication

1 reference

12 December 2020

Proceedings: Central stimulant action of fenfluramine in the rat.

1 reference

12 December 2020

Does fenfluramine act via norfenfluramine?

1 reference

12 December 2020

Comparison of anorexigenic and behavioral potency of phenylethylamines

1 reference

12 December 2020

The effect of acute administration of (meta trifluoro methyl-phenyl)-1-(benzoyl oxy) ethyl amino-2-propane (780 SE) and fenfluramine on human sleep

1 reference

12 December 2020

Fenfluramine-induced ultrastructural alterations in tissues of rats and guinea pigs.

1 reference

12 December 2020

Unusual effect of fenfluramine

1 reference

12 December 2020

Effects of caloric restriction and fenfluramine on weight loss and personality profiles of patients with long standing obesity

1 reference

12 December 2020

Effect of fenfluramine on certain enzymes and on skin and amniotic cells in tissue culture

1 reference

12 December 2020

10.2165/00003495-197510040-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

20 September 2017

0 references

1 reference