(Q34118450)

31 July 2017

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title

Immune mechanisms that regulate susceptibility to autoimmune type I diabetes (English)

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31 July 2017

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Singh B

1

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31 July 2017

Delovitch TL

series ordinal

2

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31 July 2017

publication date

1 December 2000

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Clinical Reviews in Allergy & Immunology

31 July 2017

published in

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31 July 2017

volume

19

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31 July 2017

issue

3

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31 July 2017

page(s)

247-264

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Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation?

31 July 2017

cites work

1 reference

12 December 2020

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes

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12 December 2020

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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12 December 2020

A unified hypothesis for the complex genetics of HLA associations with IDDM.

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12 December 2020

Role of viruses in the pathogenesis of IDDM.

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12 December 2020

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

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12 December 2020

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

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12 December 2020

Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice

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12 December 2020

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

1 reference

12 December 2020

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

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12 December 2020

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

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12 December 2020

Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat

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12 December 2020

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

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12 December 2020

Dendritic cells and tolerance induction.

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12 December 2020

Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

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12 December 2020

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

1 reference

12 December 2020

Serologic evidence of an association between enteroviruses and the onset of type 1 diabetes mellitus. Pittsburgh Diabetes Research Group

1 reference

12 December 2020

Prevention of autoimmune type I diabetes by CD4+ suppressor T cells in superantigen-treated non-obese diabetic mice

1 reference

12 December 2020

T-cell responses to autoantigens in IDDM. The search for the Holy Grail

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12 December 2020

Oral administration of human insulin to NOD mice generates CD4+ T cells that suppress adoptive transfer of diabetes

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12 December 2020

Cell death mediators in autoimmune diabetes--no shortage of suspects

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12 December 2020

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

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12 December 2020

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

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12 December 2020

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

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12 December 2020

Insulin-dependent diabetes mellitus

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12 December 2020

CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes

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12 December 2020

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

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12 December 2020

Absolute requirement of macrophages for the development and activation of beta-cell cytotoxic CD8+ T-cells in T-cell receptor transgenic NOD mice

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12 December 2020

Characterization of novel T-cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice

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12 December 2020

T helper cell subsets in insulin-dependent diabetes

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12 December 2020

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

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12 December 2020

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

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12 December 2020

Monoclonal antibody to rubella virus capsid protein recognizes a beta-cell antigen

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12 December 2020

Insulin-dependent diabetes mellitus: the hypothesis of molecular mimicry between islet cell antigens and microorganisms

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12 December 2020

Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis

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12 December 2020

Peripheral deletion of antigen-reactive T cells in oral tolerance.

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12 December 2020

Long-term survival of syngeneic islet grafts in BCG-treated diabetic NOD mice can be reversed by cyclophosphamide

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12 December 2020

Protection against autoimmune diabetes with oral insulin is associated with the presence of IL-4 type 2 T-cells in the pancreas and pancreatic lymph nodes

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12 December 2020

Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277

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12 December 2020

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

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12 December 2020

Immunization With the Larger Isoform of Mouse Glutamic Acid Decarboxylase (GAD67) Prevents Autoimmune Diabetes in NOD Mice

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12 December 2020

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele

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12 December 2020

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

12 December 2020

Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen

1 reference

12 December 2020

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

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12 December 2020

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders

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12 December 2020

Characterization of immunodominant peptide determinants of IDDM-associated autoantigens in the NOD mouse.

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12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

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12 December 2020

Molecular basis for HLA-DQ associations with IDDM.

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12 December 2020

Insulin prophylaxis in individuals at high risk of type I diabetes

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12 December 2020

Protective and destructive effects of microbial infection in insulin-dependent diabetes mellitus

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12 December 2020

Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

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12 December 2020

Altered Thymic and Peripheral T-Lymphocyte Repertoire Preceding Onset of Diabetes in NOD Mice

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12 December 2020

RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice

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12 December 2020

Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens

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12 December 2020

Scientific and political impediments to successful islet transplantation

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12 December 2020

Role of T-cell anergy and suppression in susceptibility to IDDM.

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12 December 2020

Prevention of cyclophosphamide-induced and spontaneous diabetes in NOD/Shi/Kbe mice by anti-MHC class I Kd monoclonal antibody

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12 December 2020

Interleukin-4 deficiency does not exacerbate disease in NOD mice

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12 December 2020

Population based study of prevalence of islet cell autoantibodies in monozygotic and dizygotic Danish twin pairs with insulin dependent diabetes mellitus

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12 December 2020

Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection

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12 December 2020

Prevention of Recurrence of IDDM in Islet-Transplanted Diabetic NOD Mice by Adjuvant Immunotherapy

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12 December 2020

A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes

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12 December 2020

Retroviral superantigens and type 1 diabetes mellitus

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12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

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12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

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12 December 2020

Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy

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12 December 2020

Impaired yield, phenotype, and function of monocyte-derived dendritic cells in humans at risk for insulin-dependent diabetes.

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12 December 2020

Natural killer activating receptors trigger interferon gamma secretion from T cells and natural killer cells

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12 December 2020

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

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12 December 2020

Immunization of diabetes-prone or non-diabetes-prone mice with GAD65 does not induce diabetes or islet cell pathology

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12 December 2020

The role of enteroviral infections in the development of IDDM: limitations of current approaches.

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12 December 2020

Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma

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12 December 2020

Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?

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12 December 2020

Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse

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12 December 2020

Genetics of type 1 diabetes

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12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

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12 December 2020

Nitric oxide in autoimmune disease: cytotoxic or regulatory mediator?

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12 December 2020

Altered cytokine activity in adjuvant inhibition of autoimmune diabetes

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12 December 2020

Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes

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12 December 2020

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

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12 December 2020

Breaking self-tolerance in nonobese diabetic mice

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12 December 2020

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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12 December 2020

The IDDMK(1,2)22 retrovirus is not detectable in either mRNA or genomic DNA from patients with type 1 diabetes

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12 December 2020

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

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12 December 2020

Influence of microbial agents on the development and prevention of autoimmune diabetes

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12 December 2020

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation

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12 December 2020

Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance

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12 December 2020

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

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12 December 2020

Induction of type I diabetes by Kilham's rat virus in diabetes-resistant BB/Wor rats

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12 December 2020

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

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12 December 2020

Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E.

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12 December 2020

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

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12 December 2020

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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12 December 2020

Genetic analysis of susceptibility to type 1 diabetes

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12 December 2020

Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta-cell antigens

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12 December 2020

Modulation of insulin-dependent diabetes mellitus (IDDM) in NOD mice by autoreactive T cells

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12 December 2020

Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo

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12 December 2020

Diabetogenic T-cell clones

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12 December 2020

Autoimmunity. The pathogen connection

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12 December 2020

Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment.

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12 December 2020

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

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12 December 2020

MHC class-II molecules and autoimmunity

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12 December 2020

Mouse CD1-specific NK1 T cells: development, specificity, and function

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12 December 2020

Failure to detect genomic viral sequences in pancreatic tissues from two children with acute-onset diabetes mellitus.

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12 December 2020

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

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12 December 2020

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

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12 December 2020

Superantigens of mouse mammary tumour virus: implications for diabetes?

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Beta-cell destruction may be a late consequence of the autoimmune process in nonobese diabetic mice

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12 December 2020

IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function

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12 December 2020

CD28/B7 regulation of autoimmune diabetes

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12 December 2020

Cyclophosphamide treatment of female non-obese diabetic mice causes enhanced expression of inducible nitric oxide synthase and interferon-gamma, but not of interleukin-4

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12 December 2020

Prevention of type I diabetes in NOD mice by adjuvant immunotherapy

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12 December 2020

Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice

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12 December 2020

Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets

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12 December 2020

Induction of tolerance by IL-10-treated dendritic cells

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12 December 2020

Epitope dominance: evidence for reciprocal determinant spreading to glutamic acid decarboxylase in non-obese diabetic mice

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12 December 2020

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

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12 December 2020

Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy

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12 December 2020

T cell tolerance by clonal elimination in the thymus

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12 December 2020

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice

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12 December 2020

Superantigens in insulin-dependent diabetes mellitus

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12 December 2020

Insulin-dependent diabetes mellitus as an autoimmune disease

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12 December 2020

Mapping of novel genes predisposing or protecting diabetes development in the BB/OK rat.

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12 December 2020

Genetic control of autoimmune diabetes in the NOD mouse

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

The role of Fas in autoimmune diabetes

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12 December 2020

No evidence for association between IDDMK(1,2)22, a novel isolated retrovirus, and IDDM.

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12 December 2020

Identifiers

DOI

10.1385/CRIAI:19:3:247

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Dimensions Publication ID

31 July 2017

1047709832

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Fatcat ID

release_xglwbu4qh5a4pblysudo4j2izq

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Fatcat

https://api.fatcat.wiki/v0/release/xglwbu4qh5a4pblysudo4j2izq

24 November 2022

mapped directly with Wikidata item

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