(Q35532733)

8 August 2017

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title

Genetic analysis of susceptibility to type 1 diabetes (English)

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8 August 2017

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1

J. A. Todd

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PubMed ID

1440197

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1440197

26 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

PubMed ID

1440197

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1440197

26 September 2022

publication date

1 January 1992

1 reference

Seminars in Immunopathology

8 August 2017

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8 August 2017

14

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8 August 2017

1

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8 August 2017

33-58

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https://scigraph.springernature.com/pub.10.1007/bf00197131

8 August 2017

0 references

cites work

Maps of linkage and synteny homologies between mouse and man.

1 reference

12 December 2020

Primary association of HLA-DQw8 with type I diabetes in DR4 patients

1 reference

12 December 2020

The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese

1 reference

12 December 2020

Physical map of the human HLA region

1 reference

12 December 2020

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1 reference

12 December 2020

Identification of a polymorphic variant associated with HLA-DQw3 and characterized by specific restriction sites within the DQ beta-chain gene.

1 reference

12 December 2020

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

12 December 2020

Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types

1 reference

12 December 2020

HLA-linked immune suppression in humans

1 reference

12 December 2020

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

1 reference

12 December 2020

Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells

1 reference

12 December 2020

Insulin-dependent diabetes mellitus: HLA-DR and -DQ genotyping in three ethnic groups

1 reference

12 December 2020

A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules

1 reference

12 December 2020

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

1 reference

12 December 2020

Association of susceptibility to spontaneous diabetes in rat with genes of major histocompatibility complex

1 reference

12 December 2020

Chromosome mapping with DNA markers

1 reference

12 December 2020

F protein and immune suppression genes.

1 reference

12 December 2020

The genetic predisposition to fibrocalculous pancreatic diabetes

1 reference

12 December 2020

Trans-racial studies implicate HLA-DQ as a component of genetic susceptibility to type 1 (insulin-dependent) diabetes.

1 reference

12 December 2020

Immunostimulation circumvents diabetes in NOD/Lt mice

1 reference

12 December 2020

DR2+ haplotypes in insulin-dependent diabetes: analysis of DNA restriction fragment length polymorphisms

1 reference

12 December 2020

Mechanisms of pancreatic beta-cell destruction in type I diabetes

1 reference

12 December 2020

The DR3(w18),DQw4 haplotype differs from DR3(w17),DQw2 haplotypes at multiple class II loci

1 reference

12 December 2020

T lymphocyte clones recognizing an HLA-DQw3.2-associated epitope involving residue 57 on the DQ beta chain

1 reference

12 December 2020

A new cluster of genes within the human major histocompatibility complex

1 reference

12 December 2020

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

1 reference

12 December 2020

HLA-DQ antigens and DQ beta amino acid 57 of Japanese patients with insulin-dependent diabetes mellitus: detection of a DRw8DQw8 haplotype

1 reference

12 December 2020

The HLA-D associations of type 1 (insulin-dependent) diabetes in Punjabi Asians in the United Kingdom

1 reference

12 December 2020

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

1 reference

12 December 2020

A family study of the association between insulin dependent diabetes mellitus, autoantibodies and the HLA system

1 reference

12 December 2020

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility

1 reference

12 December 2020

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus

1 reference

12 December 2020

The significance of the concordance rate for type 1 (insulin-dependent) diabetes in identical twins.

1 reference

12 December 2020

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses

1 reference

12 December 2020

HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals

1 reference

12 December 2020

The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus.

1 reference

12 December 2020

Insulin-dependent diabetes--associated HLA-D region encoded determinants

1 reference

12 December 2020

Measuring the genetic contribution of a single locus to a multilocus disease

1 reference

12 December 2020

Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice

1 reference

12 December 2020

Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus

1 reference

12 December 2020

Killing of antigen-reactive B cells by class II- restricted, soluble antigen–specific CD8+ cytolytic T lymphocytes

1 reference

12 December 2020

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

1 reference

12 December 2020

Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells. Transfer of diabetes and insulitis to nondiabetic (NOD X B10) F1 mice with bone marrow cells from NOD mice

1 reference

12 December 2020

An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

1 reference

12 December 2020

Pancreatic islet-cell damage in children with fatal viral infections

1 reference

12 December 2020

Acquisition of immunologic self-tolerance

1 reference

12 December 2020

An increased risk of insulin-dependent diabetes mellitus (IDDM) among HLA-DR4,DQw8/DRw8,DQw4 heterozygotes

1 reference

12 December 2020

A newly characterized HLA DQ beta allele associated with pemphigus vulgaris.

1 reference

12 December 2020

Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus

1 reference

12 December 2020

Aberrant expression of class II major histocompatibility complex molecules by B cells and hyperexpression of class I major histocompatibility complex molecules by insulin containing islets in type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

Molecular organization of the DQ subregion (DO-DX-DV-DQ) of the human MHC and its evolutionary implications

1 reference

12 December 2020

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

1 reference

12 December 2020

An analysis of variation in the long-range genomic organization of the human major histocompatibility complex class II region by pulsed-field gel electrophoresis

1 reference

12 December 2020

HLA-DR and -DQ DNA genotyping in insulin-dependent diabetes patients in South India

1 reference

12 December 2020

Destruction of pancreatic islet cells by cytotoxic T lymphocytes in nonobese diabetic mice

1 reference

12 December 2020

Polymorphism of the HLA-D region in American blacks. A DR3 haplotype generated by recombination

1 reference

12 December 2020

Association of HLA-DQw3 (TA10-) with type I diabetes occurs with DR3/4 but not DR1/4 patients

1 reference

12 December 2020

The susceptibility to insulin-dependent diabetes mellitus is associated with C4 allotypes independently of the association with HLA-DQ alleles in HLA-DR3,4 heterozygotes

1 reference

12 December 2020

Recombination sites in the HLA class II region are haplotype dependent

1 reference

12 December 2020

HL-A antigens and diabetes mellitus.

1 reference

12 December 2020

Effects of cyclosporine A on T cell development and clonal deletion

1 reference

12 December 2020

Prevention of type I diabetes in nonobese diabetic mice by virus infection

1 reference

12 December 2020

Thymus transplantation and disease prevention in the diabetes-prone Bio-Breeding rat.

1 reference

12 December 2020

HLA-DQ beta non-ASP-57 allele and incidence of diabetes in China and the USA

1 reference

12 December 2020

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

1 reference

12 December 2020

Genetic control of diabetes and insulitis in the nonobese diabetic mouse. Pedigree analysis of a diabetic H-2nod/b heterozygote

1 reference

12 December 2020

TNF-alpha gene polymorphisms in type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

The insulin gene and susceptibility to IDDM.

1 reference

12 December 2020

HLA and insulin gene associations with IDDM.

1 reference

12 December 2020

Two genes required for diabetes in BB rats. Evidence from cyclical intercrosses and backcrosses

1 reference

12 December 2020

Human T cell clones with specificity for insulinoma cell antigens

1 reference

12 December 2020

Only one DQ-beta restriction fragment pattern of each DR specificity is associated with insulin-dependent diabetes

1 reference

12 December 2020

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

12 December 2020

Assessing the role of HLA-linked and unlinked determinants of disease

1 reference

12 December 2020

Genes predisposing to IDDM in multiplex families

1 reference

12 December 2020

HLA DQ beta 3.2 identifies subtypes of DR4+ haplotypes permissive for IDDM.

1 reference

12 December 2020

HLA-DR4 in insulin-dependent diabetic parents and their diabetic offspring: a clue to dominant inheritance

1 reference

12 December 2020

Intracellular competition for component chains determines class II MHC cell surface phenotype

1 reference

12 December 2020

Restriction fragment length polymorphism of HLA and non-HLA genes in DR3/4 heterozygous Danish insulin-dependent diabetic patients and healthy individuals: reassessment of the influence of alpha DX and insulin-linked polymorphic loci, and new splits

1 reference

12 December 2020

Spontaneous cytotoxicity of macrophages against pancreatic islet cells.

1 reference

12 December 2020

Prevention of diabetes in NOD mice by injection of autoreactive T-lymphocytes

1 reference

12 December 2020

Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris

1 reference

12 December 2020

Immunology of insulin-dependent diabetes mellitus

1 reference

12 December 2020

MHC molecules and beta-cell destruction. Immune and nonimmune mechanisms

1 reference

12 December 2020

Variable number of tandem repeat (VNTR) markers for human gene mapping

1 reference

12 December 2020

Distinct macrophage subpopulations in pancreas of prediabetic BB/E rats. Possible role for macrophages in pathogenesis of IDDM

1 reference

12 December 2020

Maturity-onset diabetes of youth in black Americans

1 reference

12 December 2020

Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to type 1 (insulin-dependent) diabetes mellitus.

1 reference

12 December 2020

Geographic patterns of childhood insulin-dependent diabetes mellitus. Diabetes Epidemiology Research International Group

1 reference

12 December 2020

Genetic analysis of IDDM: summary of GAW5 IDDM results

1 reference

12 December 2020

Identification of the cystic fibrosis gene: genetic analysis

1 reference

12 December 2020

Molecular diversity of HLA-DR4 haplotypes

1 reference

12 December 2020

Molecular characterization of MHC class II antigens (beta 1 domain) in the BB diabetes-prone and -resistant rat.

1 reference

12 December 2020

Disease associations. Chance, artifact, or susceptibility genes?

1 reference

12 December 2020

Structural variation among major histocompatibility complex class-II genes which predispose to autoimmunity

1 reference

12 December 2020

A molecular basis for genetic susceptibility to insulin-dependent diabetes mellitus

1 reference

12 December 2020

Lilly lecture 1986. Genes, generator of diversity, glycoconjugates, and autoimmune beta-cell insufficiency in type I diabetes.

1 reference

12 December 2020

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

1 reference

12 December 2020

T-lymphocyte clone specific for pancreatic islet antigen

1 reference

12 December 2020

HLA-DR2-associated Dw subtypes correlate with RFLP clusters: most DR2 IDDM patients belong to one of these clusters

1 reference

12 December 2020

HLA-DQ rather than HLA-DR region might be involved in dominant nonsusceptibility to diabetes

1 reference

12 December 2020

HLA-DR 3 is associated with a more slowly progressive form of Type 1 (insulin-dependent) diabetes

1 reference

12 December 2020

Inherited susceptibility to insulin-dependent diabetes is associated with HLA-DR1, while DR5 is protective

1 reference

12 December 2020

Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells

1 reference

12 December 2020

HLA-DQ system and insulin-dependent diabetes mellitus in Japanese: does it contribute to the development of IDDM as it does in Caucasians?

1 reference

12 December 2020

Class II HLA DNA polymorphisms in type 1 (insulin-dependent) diabetic patients of north Indian origin

1 reference

12 December 2020

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

1 reference

12 December 2020

Coxsackie B virus assays in IDDM families: the GAW5 data on antibody prevalence

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

1 reference

12 December 2020

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping.

1 reference

12 December 2020

ASSOCIATION OF CYTOMEGALOVIRUS INFECTION WITH AUTOIMMUNE TYPE 1 DIABETES

1 reference

12 December 2020

Development of autoimmune insulitis is prevented in E alpha d but not in A beta k NOD transgenic mice

1 reference

12 December 2020

V beta-specific stimulation of human T cells by staphylococcal toxins.

1 reference

12 December 2020

An allelic cluster of DQ alpha restriction fragments is associated with multiple sclerosis: evidence that a second haplotype may influence disease susceptibility

1 reference

12 December 2020

Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region

1 reference

12 December 2020

HLA and insulin-dependent diabetes: an overview

1 reference

12 December 2020

Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies

1 reference

12 December 2020

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1 reference

12 December 2020

Strong association of HLA-DR3/DRw9 heterozygosity with early-onset insulin-dependent diabetes mellitus in Chinese

1 reference

12 December 2020

HLA-DQ is epistatic to HLA-DR in controlling the immune response to schistosomal antigen in humans

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00197131

1 reference

8 August 2017

1 reference

PubMed ID

1440197