(Q34120276)

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Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter

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Europe PubMed Central

PubMed publication ID

31 July 2017

Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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1 reference

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Parkinson's disease

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based on heuristic

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toxic encephalopathy

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based on heuristic

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author name string

Alexander Storch

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Stefanie Ott

2

1 reference

Europe PubMed Central

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31 July 2017

Yu I Hwang

3

1 reference

Europe PubMed Central

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31 July 2017

Rainer Ortmann

4

1 reference

Europe PubMed Central

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31 July 2017

Andreas Hein

5

1 reference

Europe PubMed Central

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31 July 2017

Stefan Frenzel

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Kazuo Matsubara

7

1 reference

Europe PubMed Central

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31 July 2017

Shigeru Ohta

8

1 reference

Europe PubMed Central

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31 July 2017

Hans Uwe Wolf

9

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31 July 2017

Johannes Schwarz

10

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31 July 2017

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1 March 2002

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31 July 2017

Biochemical Pharmacology

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31 July 2017

63

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31 July 2017

5

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Europe PubMed Central

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31 July 2017

909-920

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

MPP+ toxicity in rat striatal slices: relationship between non-selective effects and free radical production

1 reference

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7 January 2021

Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines

1 reference

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7 January 2021

Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium

1 reference

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7 January 2021

Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group

1 reference

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7 January 2021

Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

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Prospects for new restorative and neuroprotective treatments in Parkinson's disease

1 reference

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7 January 2021

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

1 reference

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7 January 2021

Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Studies on the uptake of N-methylisoquinolinium ion into rat striatal slices using high-performance liquid chromatography with fluorimetric detection

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

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7 January 2021

Dopamine transporter and catechol-O-methyltransferase activities are required for the toxicity of 1-(3',4'-dihydroxybenzyl)-1,2,3, 4-tetrahydroisoquinoline

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Parkinsonism-inducing neurotoxin MPP+: uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

MPP+ toxicity and plasma membrane dopamine transporter: study using cell lines expressing the wild-type and mutant rat dopamine transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

1‐Benzyl‐1,2,3,4‐Tetrahydroisoquinoline as a Parkinsonism‐Inducing Agent: A Novel Endogenous Amine in Mouse Brain and Parkinsonian CSF

2 references

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

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7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic administration of 1-benzyl-1,2,3,4-tetrahydroisoquinoline, an endogenous amine in the brain, induces parkinsonism in a primate

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Parkinson's disease. First of two parts

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Association of a polymorphism in the dopamine-transporter gene with parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in parkinsonian cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

A neurotoxin N-methyl(R)salsolinol induces apoptotic cell death in differentiated human dopaminergic neuroblastoma SH-SY5Y cells

1 reference

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7 January 2021

Structural significance of azaheterocyclic amines related to Parkinson's disease for dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Inhibition of α-Ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

The route and significance of endogenous synthesis of alkaloids in animals

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

A single nucleotide polymorphism of dopamine transporter gene is associated with Parkinson's disease

1 reference

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7 January 2021

Presence of methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, derivatives of the neurotoxin isoquinoline, in parkinsonian lumbar CSF.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Presence of N-methyl-norsalsolinol in the CSF: correlations with dopamine metabolites of patients with Parkinson's disease

1 reference

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

(R)salsolinol N-methyltransferase activity increases in parkinsonian lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Tetrahydropapaveroline and its derivatives inhibit dopamine uptake through dopamine transporter expressed in HEK293 cells

1 reference

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7 January 2021

The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

1 reference

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7 January 2021

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Tetrahydroisoquinoline alkaloids: in vivo metabolites of L-dopa in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

6-Hydroxydopamine toxicity towards human SH-SY5Y dopaminergic neuroblastoma cells: independent of mitochondrial energy metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Protective effects of riluzole on dopamine neurons: involvement of oxidative stress and cellular energy metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Cytotoxicity of endogenous isoquinolines to human dopaminergic neuroblastoma SH-SY5Y cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

Alkaloids in mammalian tissues. 2. Synthesis of (+)- and (-)-1-substituted-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines

1 reference

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7 January 2021

Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea

1 reference

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7 January 2021

Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900922-4

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1016/S0006-2952(01)00922-4

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Europe PubMed Central

PubMed publication ID

31 July 2017

release_wjwfgoippfd7lakcjelxw5yp64

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https://api.fatcat.wiki/v0/release/wjwfgoippfd7lakcjelxw5yp64

24 November 2022

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PubMed publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

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