(Q34121180)

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Shifting the LDL-receptor paradigm in familial hypercholesterolemia: novel insights from recent kinetic studies of apolipoprotein B-100 metabolism

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

Shifting the LDL-receptor paradigm in familial hypercholesterolemia: novel insights from recent kinetic studies of apolipoprotein B-100 metabolism (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

hypercholesterolemia

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familial hypercholesterolemia

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2

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Gerald F Watts

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31 July 2017

author name string

P Hugh R Barrett

1

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Europe PubMed Central

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31 July 2017

publication date

1 March 2002

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Europe PubMed Central

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31 July 2017

Atherosclerosis. Supplements

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Europe PubMed Central

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31 July 2017

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1-4

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Europe PubMed Central

PubMed publication ID

31 July 2017

Atherosclerosis: The low-density lipoprotein receptor hypothesis

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7 January 2021

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Governance of the concentration of plasma LDL: a reevaluation of the LDL receptor paradigm

1 reference

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Substrate delivery as a determinant of hepatic apoB secretion

1 reference

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Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

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Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

1 reference

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inferred from DOI database lookup

The role of the LDL receptor in apolipoprotein B secretion

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Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits

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Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit

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Kinetic bases of the primary hyperlipidaemias: studies of apolipoprotein B turnover in genetically defined subjects

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ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm

1 reference

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inferred from DOI database lookup

Increased hepatic secretion of very-low-density-lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolaemia: a stable isotope study

1 reference

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Simvastatin decreases the hepatic secretion of very‐low‐density lipoprotein apolipoprotein B‐100 in heterozygous familial hypercholesterolaemia: pathophysiological and therapeutic implications

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Upregulation of cholesterol synthesis after acute reduction of low density lipoprotein by apheresis in normocholesterolaemic subjects: evidence for a threshold effect

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Low-density lipoprotein-apolipoprotein B metabolism following apheresis: simulation studies of mass changes and tracer kinetics

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Homozygous familial defective apolipoprotein B-100. Enhanced removal of apolipoprotein E-containing VLDLs and decreased production of LDLs.

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Update on low density lipoprotein receptor mutations

1 reference

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Genotype/phenotype correlations in familial hypercholesterolaemia

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Effect on plasma lipid levels of different classes of mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia

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Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins]

1 reference

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Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia

1 reference

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inferred from DOI database lookup

Delayed chylomicron remnant clearance in subjects with heterozygous familial hypercholesterolaemia.

1 reference

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HMG-CoA reductase inhibitors for treatment of hypercholesterolemia

1 reference

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Identifiers

10.1016/S1567-5688(01)00012-5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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