(Q34121376)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Human beta1-adrenergic receptor is subject to constitutive and regulated N-terminal cleavage (English)

1 reference

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6 February 2020

4

1 reference

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6 February 2020

author name string

Anna E Hakalahti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Miia M Vierimaa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Minna K Lilja

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Jussi T Tuusa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Ulla E Petäjä-Repo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

language of work or name

English

0 references

publication date

29 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

number of pages

12

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

28850-28861

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

6 February 2020

cites work

1 reference

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Phe27Cys polymorphism alters the maturation and subcellular localization of the human delta opioid receptor

28 July 2018

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Structure of a beta1-adrenergic G-protein-coupled receptor

28 July 2018

1 reference

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Structural diversity of G protein-coupled receptors and significance for drug discovery

28 July 2018

1 reference

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Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies

28 July 2018

1 reference

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Regulation of GPCRs by endocytic membrane trafficking and its potential implications

28 July 2018

1 reference

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Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin.

28 July 2018

1 reference

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G protein-coupled receptor sorting to endosomes and lysosomes

28 July 2018

1 reference

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Opioid receptor pharmacological chaperones act by binding and stabilizing newly synthesized receptors in the endoplasmic reticulum

28 July 2018

1 reference

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Conformation state-sensitive antibodies to G-protein-coupled receptors

28 July 2018

1 reference

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Cardiac adrenoceptors: physiological and pathophysiological relevance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Shedding light on ADAM metalloproteinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Inefficient maturation of the rat luteinizing hormone receptor. A putative way to regulate receptor numbers at the cell surface

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

ADAMs: key components in EGFR signalling and development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Beta-adrenergic receptors and their interacting proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Differences in endosomal targeting of human (beta)1- and (beta)2-adrenergic receptors following clathrin-mediated endocytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Resistance of the human beta 1-adrenergic receptor to agonist-mediated down-regulation. Role of the C terminus in determining beta-subtype degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

A monoclonal thyroid-stimulating antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Complexity of agonist- and cyclic AMP-mediated downregulation of the human beta 1-adrenergic receptor: role of internalization, degradation, and mRNA destabilization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Seven-transmembrane-spanning receptors and heart function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.

28 July 2018

1 reference

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Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

O-Glycosylation of the V2 vasopressin receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Elimination of the O-linked glycosylation site at Thr 104 results in the generation of a soluble human-transferrin receptor.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

International Union of Pharmacology nomenclature of adrenoceptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

The avian beta-adrenergic receptor: primary structure and membrane topology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Cloning of the cDNA for the human beta 1-adrenergic receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Distinct regulation of beta 1- and beta 2-adrenergic receptors in Chinese hamster fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

The PDZ binding motif of the beta 1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Regulated shedding of PAR1 N-terminal exodomain from endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Structural requirements for V2 vasopressin receptor proteolytic cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Does thyrotropin cleave its cognate receptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Human bradykinin B2 receptor sialylation and N-glycosylation participate with disulfide bonding in surface receptor dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

O-Glycosylation of G-protein-coupled receptor, octopus rhodopsin. Direct analysis by FAB mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149989

Distinct receptor domains determine subtype-specific coupling and desensitization phenotypes for human beta1- and beta2-adrenergic receptors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937912

Proteolysis-associated deglycosylation of beta 1-adrenergic receptor in turkey erythrocytes and membranes

28 October 2018

1 reference

12 December 2020

Purification and characterization of bovine lung endothelin receptor

1 reference

12 December 2020

A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration

1 reference

12 December 2020

Ligand-induced cleavage of the V2 vasopressin receptor by a plasma membrane metalloproteinase

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.149989

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587416%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

20587416

1 reference