(Q34122846)

English

Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

ChEBI release 2020-05-28

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

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author name string

Pankaj Gupta

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Christine Alvey

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Rong Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Martin E Dowty

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Odette A Fahmi

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Robert L Walsky

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Richard J Riese

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Sriram Krishnaswami

8

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

1 July 2012

1 reference

Europe PubMed Central

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31 July 2017

British Journal of Clinical Pharmacology

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Europe PubMed Central

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31 July 2017

74

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Europe PubMed Central

PubMed publication ID

31 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

109-115

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Evaluation of models for predicting drug-drug interactions due to induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

Noninvasive tests of CYP3A enzymes

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 July 2018

Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Validated assays for human cytochrome P450 activities

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Comparison of midazolam and simvastatin as cytochrome P450 3A probes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Exposure-response modeling using latent variables for the efficacy of a JAK3 inhibitor administered to rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Guide to Receptors and Channels (GRAC), 4th Edition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2012.04168.X

21 January 2018

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 October 2018

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3394134

28 October 2018

Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22233204

12 December 2020

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Identifiers

10.1111/J.1365-2125.2012.04168.X

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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