(Q37800932)

23 August 2017

title

Evaluation of models for predicting drug-drug interactions due to induction (English)

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23 August 2017

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Odette A Fahmi

1

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23 August 2017

Sharon L Ripp

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

1 November 2010

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Expert Opinion on Drug Metabolism & Toxicology

23 August 2017

published in

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23 August 2017

volume

6

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23 August 2017

issue

11

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23 August 2017

page(s)

1399-1416

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Rifampin and rifabutin drug interactions: an update

23 August 2017

cites work

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

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Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects

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Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes

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In vitro and in vivo induction of cytochrome p450: a survey of the current practices and recommendations: a pharmaceutical research and manufacturers of america perspective

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Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line

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Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

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Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction

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Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions

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Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome p450 induction potential of drugs in vivo in humans

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HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans

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Prediction of drug-drug interactions from in vitro induction data: application of the relative induction score approach using cryopreserved human hepatocytes

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Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction

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Comparison of different algorithms for predicting clinical drug-drug interactions, based on the use of CYP3A4 in vitro data: predictions of compounds as precipitants of interaction

21 January 2018

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Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction

21 January 2018

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A combined model for predicting CYP3A4 clinical net drug-drug interaction based on CYP3A4 inhibition, inactivation, and induction determined in vitro

21 January 2018

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Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells

21 January 2018

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Comparative investigation of the pharmacokinetics of bosentan in Caucasian and Japanese healthy subjects

21 January 2018

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Clinical pharmacology of bosentan, a dual endothelin receptor antagonist

21 January 2018

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Carbamazepine markedly reduces serum concentrations of simvastatin and simvastatin acid

21 January 2018

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Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males

21 January 2018

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Pharmacokinetic interactions with rifampicin : clinical relevance

21 January 2018

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10.1517/17425255.2010.516251

21 January 2018

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a42hbtmvtbgnrpoj5qfjk25xp4

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30 July 2022

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Fatcat ID

release_a42hbtmvtbgnrpoj5qfjk25xp4

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Fatcat

https://api.fatcat.wiki/v0/release/a42hbtmvtbgnrpoj5qfjk25xp4

mapped directly with Wikidata item

30 July 2022

based on heuristic

https://api.fatcat.wiki/v0/release/a42hbtmvtbgnrpoj5qfjk25xp4

1 reference