(Q28308225)

2

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Kairui Feng

3

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Adrian Barnett

4

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Geoffrey Tucker

5

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Amin Rostami-Hodjegan

Expert Opinion on Drug Metabolism & Toxicology

6

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language of work or name

English

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publication date

February 2009

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published in

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volume

5

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issue

2

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page(s)

211-23

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cites work

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Pharmacometrics at FDA: evolution and impact on decisions

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ADMET in silico modelling: towards prediction paradise?

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The emerging importance of predictive ADME simulation in drug discovery

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Prediction of in vivo drug clearance from in vitro data. I: impact of inter-individual variability

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Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices

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Pharmacokinetic-pharmacogenetic modelling in the detection of polymorphisms in xenobiotic metabolism

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Backtracking booze with Bayes--the retrospective interpretation of blood alcohol data

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Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

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Time-dependent CYP inhibition

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Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction

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Analysis of solvent central nervous system toxicity and ethanol interactions using a human population physiologically based kinetic and dynamic model

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Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

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Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition

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Volume of distribution at steady state for a linear pharmacokinetic system with peripheral elimination

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Differential-Algebraic Equations

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Investigation of the utility of published in vitro intrinsic clearance data for prediction of in vivo clearance

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